Quality of life in obstructive sleep apnea is related to female gender and comorbid insomnia

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dc.contributor.authorTasbakan, Mehmet Sezai
dc.contributor.authorGunduz, Canan
dc.contributor.authorPirildar, Sebnem
dc.contributor.authorBasoglu, Ozen K.
dc.date.accessioned2019-10-27T10:00:26Z
dc.date.available2019-10-27T10:00:26Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose Obstructive sleep apnea (OSA) is a common sleep disorder affecting health-related quality of life (QoL), and OSA severity is not a reliable indicator for QoL. The aim of this study was (1) to evaluate the impact of gender on QoL and (2) to identify the predictors of QoL in OSA patients. Methods World Health Organization Quality of Life Scale short form (WHOQOL-Bref) was used for evaluating QoL in OSA patients undergoing polysomnography in sleep laboratory of a university hospital. Results Out of 197 patients (age 50.4 +/- 12.1 years, AHI 38.5 +/- 28.4/h), 139 (70.6%) were men and 79.2% had moderate-to-severe OSA. Female gender, increased BMI, higher Epworth sleepiness score (ESS), and lower oxygen saturations were associated significantly with poor QoL in terms of all domains (physical, psychological, social relationship, and environmental) of WHOQOL-Bref questionnaire. The indicators of OSA severity (AHI and ODI) correlated negatively only with the physical domain. The subjects with comorbid insomnia and OSA had lower physical and social scores than subjects with no insomnia, and women with insomnia had significantly worse QoL scores in all domains than the others. In the multivariate linear regression analysis, female gender, comorbid insomnia, increased sleepiness, and higher BMI were significantly associated with poor QoL. Conclusions Female gender, comorbid insomnia, and daytime sleepiness were the outstanding factors affecting health-related QoL negatively in OSA. Besides, the impact of OSA on QoL may be explained by the presence of daytime sleepiness rather than OSA severity.en_US
dc.identifier.doi10.1007/s11325-018-1621-yen_US
dc.identifier.endpage1020en_US
dc.identifier.issn1520-9512
dc.identifier.issn1522-1709
dc.identifier.issue4en_US
dc.identifier.pmid29352360en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1013en_US
dc.identifier.urihttps://doi.org/10.1007/s11325-018-1621-y
dc.identifier.urihttps://hdl.handle.net/11454/29724
dc.identifier.volume22en_US
dc.identifier.wosWOS:000452078700016en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofSleep and Breathingen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectObstructive sleep apneaen_US
dc.subjectQuality of lifeen_US
dc.subjectGenderen_US
dc.subjectInsomniaen_US
dc.titleQuality of life in obstructive sleep apnea is related to female gender and comorbid insomniaen_US
dc.typeArticleen_US

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