Comparison of qSOFA, SIRS, and NEWS scoring systems for diagnosis, mortality, and morbidity of sepsis in emergency department

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dc.authoridYalçınlı, Sercan/0000-0003-1780-8391
dc.authoridODUNCU, ALİ FUAT/0000-0003-0056-2962
dc.authorwosidYalçınlı, Sercan/ABG-2186-2020
dc.authorwosidODUNCU, ALİ FUAT/ABE-6383-2021
dc.contributor.authorOduncu, Ali Fuat
dc.contributor.authorKiyan, Guclu Selahattin
dc.contributor.authorYalcinli, Sercan
dc.date.accessioned2023-01-12T19:54:21Z
dc.date.available2023-01-12T19:54:21Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractPurpose: This study was aimed to compare the quick Sequential Organ Failure Assessment (qSOFA), Systemic Inflammatory Response Syndrome (SIRS), and National Early Warning Score (NEWS) scoring systems for diagnosing sepsis and predicting mortality and morbidity. Patients and methods: A prospective study was designed. qSOFA, SIRS, and NEWS scores were calculated at the admission. The diagnosis of sepsis was made with SOFA scoring initially. The morbidity and mortality of the patients were identified during follow-up. Also, the sensitivity, specificity, negative predictive value, and positive predictive value of three scoring systems were calculated. The scoring systems were compared with ROC analysis. Results: A total of 463 patients were evaluated. There were 287 (62.0%) patients diagnosed with sepsis, and septic shock occurred in 64 (13.8%) of patients. Seven-day mortality rate was 8.4% (n = 39), 30-day mortality rate was 18.1% (n = 84). The sensitivity for qSOFA, SIRS, and NEWS for diagnosis of sepsis was 23%, 77%, 58%, and specificity was 99%, 35%, 81% respectively. The sensitivity of the qSOFA, SIRS and NEWS scoring systems for mortality was 39%, 82%, 77% and specificity 91%, 29%, and 64%, respectively. AUROC values for mortality detected as NEWS = 0.772, qSOFA = 0.758, SIRS = 0.542. According to the ROC analysis, the SIRS system was significantly less useful than the qSOFA and NEWS system in the diagnosis of sepsis and mortality (p < 0.0001). Conclusion: NEWS and qSOFA scoring systems have similar prognosis in both diagnosing sepsis and predicting mortality and both are superior to SIRS. (c) 2021 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2021.04.006
dc.identifier.endpage59en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.pmid33839632en_US
dc.identifier.startpage54en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2021.04.006
dc.identifier.urihttps://hdl.handle.net/11454/76383
dc.identifier.volume48en_US
dc.identifier.wosWOS:000701895500008en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSepsisen_US
dc.subjectSIRSen_US
dc.subjectqSOFAen_US
dc.subjectNEWSen_US
dc.subjectEmergency roomen_US
dc.subjectMortalityen_US
dc.subjectInternational Consensus Definitionsen_US
dc.subjectIn-Hospital Mortalityen_US
dc.subjectOrgan Failureen_US
dc.subjectSeptic Shocken_US
dc.subjectPredicting Mortalityen_US
dc.subjectPrognostic Accuracyen_US
dc.subjectSofa Scoresen_US
dc.subjectCriteriaen_US
dc.subjectCareen_US
dc.subjectInfectionen_US
dc.titleComparison of qSOFA, SIRS, and NEWS scoring systems for diagnosis, mortality, and morbidity of sepsis in emergency departmenten_US
dc.typeArticleen_US

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