Multicenter Analysis of Gestational Trophoblastic Neoplasia in Turkey

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dc.contributor.authorOzalp, Sabit Sinan
dc.contributor.authorTelli, Elcin
dc.contributor.authorOge, Tufan
dc.contributor.authorTulunay, Gokhan
dc.contributor.authorBoran, Nurettin
dc.contributor.authorTuran, Taner
dc.contributor.authorYenen, Mufit
dc.contributor.authorKurdoglu, Zehra
dc.contributor.authorOzler, Ali
dc.contributor.authorYuce, Kunter
dc.contributor.authorUlker, Volkan
dc.contributor.authorArvas, Macit
dc.contributor.authorDemirkiran, Fuat
dc.contributor.authorBese, Tugan
dc.contributor.authorTokgozoglu, Nedim
dc.contributor.authorOnan, Anil
dc.contributor.authorSanci, Muzaffer
dc.contributor.authorGokcu, Mehmet
dc.contributor.authorTosun, Gokhan
dc.contributor.authorDikmen, Yilmaz
dc.contributor.authorOzsaran, Aydin
dc.contributor.authorTerek, Mustafa Cosan
dc.contributor.authorAkman, Levent
dc.contributor.authorYetimalar, Hakan
dc.contributor.authorKilic, Derya Sakarya
dc.contributor.authorGungor, Tayfun
dc.contributor.authorOzgu, Emre
dc.contributor.authorYildiz, Yunus
dc.contributor.authorKokcu, Arif
dc.contributor.authorKefeli, Mehmet
dc.contributor.authorKuruoglu, Serkan
dc.contributor.authorYuksel, Hasan
dc.contributor.authorGuvenal, Tevfik
dc.contributor.authorHasdemir, Pinar Solmaz
dc.contributor.authorOzcelik, Bulent
dc.contributor.authorSerin, Serdar
dc.contributor.authorDolanbay, Mehmet
dc.contributor.authorArioz, Dagistan Tolga
dc.contributor.authorTuncer, Nadire
dc.contributor.authorBozkaya, Hasan
dc.contributor.authorGuven, Suleyman
dc.contributor.authorKulaksiz, Deniz
dc.contributor.authorVarol, Fusun
dc.contributor.authorYanik, Ali
dc.contributor.authorOgurlu, Gonca
dc.contributor.authorSimsek, Tayyup
dc.contributor.authorToptas, Tayfun
dc.contributor.authorDogan, Selen
dc.contributor.authorCamuzoglu, Hakan
dc.contributor.authorApi, Murat
dc.contributor.authorGuzin, Kadir
dc.contributor.authorCaliskan, Eray
dc.contributor.authorDoger, Emek
dc.contributor.authorCakmak, Bulent
dc.contributor.authorIlhan, Tolgay Tuyan
dc.date.accessioned2019-10-27T22:05:50Z
dc.date.available2019-10-27T22:05:50Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: To evaluate the incidence, diagnosis and management of GTN among 28 centers in Turkey. Materials and Methods: A retrospective study was designed to include GTN patients attending 28 centers in the 10-year period between January 2003 and May 2013. Demographical characteristics of the patients, histopathological diagnosis, the International Federation of Gynecology and Obstetrics (FIGO) anatomical and prognostic scores, use of single-agent and multi-agent chemotherapy, surgical interventions and prognosis were evaluated. Results: From 2003-2013, there were 1,173,235 deliveries and 456 GTN cases at the 28 centers. The incidence was calculated to be 0.38 per 1,000 deliveries. According to the evaluated data of 364 patients, the median age at diagnosis was 31 years (range, 15-59 years). A histopathological diagnosis was present for 45.1% of the patients, and invasive mole, choriocarcinoma and PSTTs were diagnosed in 22.3% (n=81), 18.1% (n=66) and 4.7% (n=17) of the patients, respectively. Regarding final prognosis, 352 (96.7%) of the patients had remission, and 7 (1.9%) had persistence, whereas the disease was mortal for 5 (1.4%) of the patients. Conclusions: Because of the differences between countries, it is important to provide national registration systems and special clinics for the accurate diagnosis and treatment of GTN.en_US
dc.identifier.doi10.7314/APJCP.2014.15.8.3625en_US
dc.identifier.endpage3628en_US
dc.identifier.issn1513-7368
dc.identifier.issue8en_US
dc.identifier.pmid24870768en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage3625en_US
dc.identifier.urihttps://doi.org/10.7314/APJCP.2014.15.8.3625
dc.identifier.urihttps://hdl.handle.net/11454/48612
dc.identifier.volume15en_US
dc.identifier.wosWOS:000338633500049en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAsian Pacific Organization Cancer Preventionen_US
dc.relation.ispartofAsian Pacific Journal of Cancer Preventionen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGestational trophoblastic diseaseen_US
dc.subjectgestational trophoblastic neoplasiaen_US
dc.subjectincidenceen_US
dc.subjectTurkeyen_US
dc.titleMulticenter Analysis of Gestational Trophoblastic Neoplasia in Turkeyen_US
dc.typeArticleen_US

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