Thyrotoxic autoimmune encephalopathy in a female patient: Only partial response to typical immunosuppressant treatment and remission after thyroidectomy

Basit Öğe Kaydı
dc.contributor.authorYuceyar, Nur
dc.contributor.authorKaradeniz, Muarnmer
dc.contributor.authorErdogan, Mehmet
dc.contributor.authorCopur, Asli
dc.contributor.authorAkgun, Aysegul
dc.contributor.authorKumral, Emre
dc.contributor.authorOzgen, Gokhan
dc.date.accessioned2019-10-27T19:34:01Z
dc.date.available2019-10-27T19:34:01Z
dc.date.issued2007
dc.departmentEge Üniversitesien_US
dc.description.abstractHashimoto's encephalopathy (HE) is a rare immune-mediated encephalopathy developing in patients with high serum concentrations of anti-thyroid antibodies usually in an euthyroid or hypothyroid state. We report a 31-year-old female patient with thyrotoxic HE whose daughter has been followed up with the same diagnosis. Suboptimal response was observed with intravenous methylprednisolone (IVMP), intravenous immunoglobulin (IVIG) and plasmapheresis. Reduction of the anti-thyroid auto-antibody concentrations marked the patient's improvement in each episode. She relapsed under oral immunosuppressive therapy. After removing the thyroid tissue, full recovery has been achieved for the last 18 months. These data may contribute to clarification of the pathogenetic role of anti-thyroid antibodies in HE. Thyroidectomy can be considered as one of the treatment options especially in thyrotoxic HE patients with uncontrolled relapses. Our patient is the first reported HE case with a family history. Genetic background can underlie the etiopathogenesis of HE as is the case in other autoimmune disorders. (C) 2007 Elsevier B.V All rights reserved.en_US
dc.identifier.doi10.1016/j.clineuro.2007.02.006en_US
dc.identifier.endpage462en_US
dc.identifier.issn0303-8467
dc.identifier.issue5en_US
dc.identifier.pmid17395366en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage458en_US
dc.identifier.urihttps://doi.org/10.1016/j.clineuro.2007.02.006
dc.identifier.urihttps://hdl.handle.net/11454/39564
dc.identifier.volume109en_US
dc.identifier.wosWOS:000246761000016en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofClinical Neurology and Neurosurgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectautoimmuneen_US
dc.subjectencephalopathyen_US
dc.subjectfamily historyen_US
dc.subjectgeneticen_US
dc.subjectHashimoto'sen_US
dc.subjectthyroiditisen_US
dc.subjectthyrotoxicosisen_US
dc.titleThyrotoxic autoimmune encephalopathy in a female patient: Only partial response to typical immunosuppressant treatment and remission after thyroidectomyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayın Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu