Dieulafoy’s lesion as a rare cause of gastrointestinal bleeding: a single-center experience

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dc.contributor.authorÜnal, Nalan Gülşen
dc.contributor.authorÇelik, Ferit
dc.contributor.authorŞenkaya, Ali
dc.contributor.authorAslanov, Seymur
dc.contributor.authorÖzütemiz, Ahmet Ömer
dc.contributor.authorBuyruk, Abdullah Murat
dc.contributor.authorTekin, Fatih
dc.date.accessioned2023-01-12T20:33:20Z
dc.date.available2023-01-12T20:33:20Z
dc.date.issued2021
dc.departmentN/A/Departmenten_US
dc.description.abstractTo define the clinical characteristics of Dieulafoy’s lesion (DL),determine the localization features, and investigate endoscopic treatments and their results. This retrospectivestudy included 20 patients who presented to the Department of Gastroenterology due to gastrointestinal (GI) bleeding between January 2015 and December 2019 andwere diagnosed with DL. Age, gender, comorbidities, medications used, presentation findings, hemoglobin and hematocrit values at the time of presentation, number andtype of transfusions if applied, length of hospitalization in days, mortality/survival, and endoscopic procedure parameters, including the number of procedures, localizationof DL, type of bleeding stigmata, and the applied technique were recorded for all patients. Ten (50%) of the patients were women, and the mean age of all patients were66.8±17.8 years. One or more comorbidities were present in 90% of the patients. The use of acetyl salicylic acid (ASA) was present in five (25%) patients, ASA+ clopidogrelin five (25%), warfarin in two (10%), and non-steroidal anti-inflammatory drugs in two (10%). The most common complaint was observed to be hematemesis and/ormelena in 16 patients (80%). DL was most frequently seen in the stomach (n=10; 50%) where it was most commonly located in the proximal corpus (n=6; 60%). The mostprevalent bleeding stigma was active bleeding, which was seen in nine (45%) patients during endoscopy. Eight (40%) patients received endoscopic treatment combinedwith a mechanical method, and nine (45%) patients only received a mechanical treatment (endoscopic band ligation or hemoclip). The median number of hospitalizationswas five days (2-22). Transfusion was required by 13 patients (65%). The mortality rate was determined as 5%. DL should be considered especially in older patients withchronic diseases who present with recurrent GI bleeding. An endoscopic examination is the first method to be applied in the diagnosis and treatment of DL. Mechanicalmethods should be prioritized in endoscopic treatment.en_US
dc.identifier.doi10.5455/medscience.2020.08.173
dc.identifier.endpage140en_US
dc.identifier.issn2147-0634
dc.identifier.issue1en_US
dc.identifier.startpage136en_US
dc.identifier.trdizinid419867en_US
dc.identifier.urihttps://doi.org/10.5455/medscience.2020.08.173
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/419867
dc.identifier.urihttps://hdl.handle.net/11454/81341
dc.identifier.volume10en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofMedicine Scienceen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.titleDieulafoy’s lesion as a rare cause of gastrointestinal bleeding: a single-center experienceen_US
dc.typeArticleen_US

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