An analytical approach based on ESI-MS, LC-MS and PCA for the quali-quantitative analysis of cycloartane derivatives in Astragalus spp.

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dc.contributor.authorNapolitano A.
dc.contributor.authorAkay S.
dc.contributor.authorMari A.
dc.contributor.authorBedir E.
dc.contributor.authorPizza C.
dc.contributor.authorPiacente S.
dc.date.accessioned2019-10-27T08:23:09Z
dc.date.available2019-10-27T08:23:09Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractAstragalus species are widely used as health foods and dietary supplements, as well as drugs in traditional medicine. To rapidly evaluate metabolite similarities and differences among the EtOH extracts of the roots of eight commercial Astragalus spp., an approach based on direct analyses by ESI-MS followed by PCA of ESI-MS data, was carried out. Successively, quali-quantitative analyses of cycloartane derivatives in the eight Astragalus spp. by LC-ESI-MSn and PCA of LC-ESI-MS data were performed. This approach allowed to promptly highlighting metabolite similarities and differences among the various Astragalus spp. PCA results from LC-ESI-MS data of Astragalus samples were in reasonable agreement with both PCA results of ESI-MS data and quantitative results. This study affords an analytical method for the quali-quantitative determination of cycloartane derivatives in herbal preparations used as health and food supplements. © 2013 Elsevier B.V.en_US
dc.identifier.doi10.1016/j.jpba.2013.06.021en_US
dc.identifier.endpage54en_US
dc.identifier.issn0731-7085
dc.identifier.pmid23876377en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage46en_US
dc.identifier.urihttps://doi.org/10.1016/j.jpba.2013.06.021
dc.identifier.urihttps://hdl.handle.net/11454/26379
dc.identifier.volume85en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofJournal of Pharmaceutical and Biomedical Analysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAstragalus genusen_US
dc.subjectCycloartanesen_US
dc.subjectESI-MSen_US
dc.subjectLC-ESI-MSen_US
dc.subjectPCAen_US
dc.titleAn analytical approach based on ESI-MS, LC-MS and PCA for the quali-quantitative analysis of cycloartane derivatives in Astragalus spp.en_US
dc.typeArticleen_US

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