Diagnostic performance of late gadolinium enhancement in the assessment of acute cellular rejection after heart transplantation

Basit Öğe Kaydı
dc.contributor.authorŞimşek, Evrim
dc.contributor.authorNalbantgil, Sanem
dc.contributor.authorCeylan, Naim
dc.contributor.authorZoghi, Mehdi
dc.contributor.authorKemal, Hatice Soner
dc.contributor.authorEngin, Çağatay
dc.contributor.authorÖzbaran, Mustafa
dc.date.accessioned2020-12-01T12:26:39Z
dc.date.available2020-12-01T12:26:39Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Allograft rejection is still an important cause of morbidity and mortality after heart transplantation (HTx). Many techniques in cardiac magnetic resonance imaging (CMR) were investigated to diagnose acute cellular rejection (ACR). However, there is not enough information about late gadolinium enhancement (LGE) in the myocardium and ACR.Methods: We prospectively analyzed our consecutive 41 heart transplant recipients who were admitted for routine endomyocardial biopsies. CMR was performed maximum 6 h before the scheduled endomyocardial biopsy. Correlation between LGE in the myocardium and ACR was investigated.Results: Twenty-seven patients showed no rejection, and nine of them had LGE in the myocardium. Fourteen patients had LGE in the left ventricle (LV), and two patients had LGE also in the right ventricle (RV). There was no correlation between LGE and ACR (p=0.879). There was no difference in the left ventricular ejection fraction (LVEF), right ventricular fractional area change (RVFAC), and cardiac ischemic time between the groups (p=0.825, p=0.370, and p=0.419, respectively). LGE in the myocardium could be due to previous rejection episodes; therefore, all patients were retrospectively searched for previous rejection grades and number of episodes. Thirty-eight of the 41 patients had a history of one ACR episode, but none of them had a statistically significant correlation with LGE (for grade 1R, p=0.964 and grade 3R, p=1) There was also no correlation between number of rejection episodes history and LGE.Conclusion: LGE is not suitable to detect ACR in heart transplant patients. LGE and the history of ACR have no correlation.en_US
dc.identifier.endpage118en_US
dc.identifier.issn2149-2263
dc.identifier.issn2149-2271
dc.identifier.issue2en_US
dc.identifier.startpage113en_US
dc.identifier.urihttps://app.trdizin.gov.tr//makale/TVRrNU5Ua3dNQT09
dc.identifier.urihttps://hdl.handle.net/11454/65655
dc.identifier.volume16en_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.relation.ispartofThe Anatolian Journal of Cardiologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectKalp ve Kalp Damar Sistemien_US
dc.titleDiagnostic performance of late gadolinium enhancement in the assessment of acute cellular rejection after heart transplantationen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu