The comparison of microscopy and real time polymerase chain reaction methods for the diagnosis of Pneumocystis Jirovecii pneumonia: evaluation of clinical parameters

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dc.contributor.authorToz, Seray
dc.contributor.authorGunduz, Cumhur
dc.contributor.authorTetik, Asli
dc.contributor.authorTasbakan, Meltem
dc.contributor.authorPullukcu, Husnu
dc.contributor.authorBacakoglu, Feza
dc.contributor.authorTasbakan, Mehmet Sezai
dc.contributor.authorGulen, Figen
dc.contributor.authorUnver, Aysegul
dc.contributor.authorTurgay, Nevin
dc.date.accessioned2019-10-27T11:19:10Z
dc.date.available2019-10-27T11:19:10Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractIntroduction: Pneumocystis jirovecii pneumonia (PCP) causes serious infections, especially in patients with immunosuppressive diseases. In this study, it was aimed to evaluate the results of samples obtained from PCP suspected patients using two different methods together with clinical data. Materials and Methods: Microscopy and real time polymerase chain reaction (real time PCR) methods were performed with bronchoalveolar lavage (BAL) samples sended to Ege University Medical Faculty Direct Parasitology Diagnostic Laboratory between March 2009 and June 2010. Demographic characteristics, clinical and laboratory data were also recorded retrospectively. The data were evaluated using the SPSS 16.0 program. Results: A total of 42 BAL samples collected from patients (24 males, mean age: 31.49 +/- 26.14) were included. There were totally 16 P. jirovecii positives either one of the tests. Sixteen and three samples were detected positive by real time PCR and microscopy, respectively. Trimethoprim-sulfamethoxazole was prescribed in 11 PCP diagnosed cases and 6 of them died. Conclusion: Today, despite the growing opportunities in diagnosis and treatment, PCP pneumonia is associated with high mortality. Careful examination of clinical data and immune status of the patients are important. Multidisciplinary approach is required for early PCP diagnosis.en_US
dc.identifier.doi10.5578/tt.58625en_US
dc.identifier.endpage226en_US
dc.identifier.issn0494-1373
dc.identifier.issue3en_US
dc.identifier.pmid29135400en_US
dc.identifier.startpage220en_US
dc.identifier.urihttps://doi.org/10.5578/tt.58625
dc.identifier.urihttps://hdl.handle.net/11454/32709
dc.identifier.volume65en_US
dc.identifier.wosWOS:000419205200007en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTurkish Assoc Tuberculosis & Thoraxen_US
dc.relation.ispartofTuberkuloz Ve Torak-Tuberculosis and Thoraxen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPneumocystis jiroveciien_US
dc.subjectpneumoniaen_US
dc.subjectreal time PCRen_US
dc.titleThe comparison of microscopy and real time polymerase chain reaction methods for the diagnosis of Pneumocystis Jirovecii pneumonia: evaluation of clinical parametersen_US
dc.typeArticleen_US

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