Asymptomatic cytomegalovirus retinitis after cardiac transplantation

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dc.contributor.authorErakgun, T
dc.contributor.authorAfrashi, F
dc.contributor.authorNalbantgil, S
dc.contributor.authorOzbaran, M
dc.contributor.authorMentes, J
dc.date.accessioned2019-10-27T18:38:14Z
dc.date.available2019-10-27T18:38:14Z
dc.date.issued2003
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To determine the prevalence and the risk factors of cytomegalovirus (CMV) retinitis after cardiac transplantation in visually asymptomatic patients. Methods: Ophthalmoscopic examinations including fundus fluorescein angiography were performed in asymptomatic patients who had cardiac transplantation at Ege University Hospital between April 1998 and June 2002 to screen for evidence of diagnostic CMV retinitis lesions to determine the prevalence in this population. Results: Thirteen patients (aged 40 +/- 12.6) who had cardiac transplantation underwent ophthalmoscopic examination 2-50 months (23.5 +/- 16.2 months; mean +/- SD) after transplantation. All recipients had positive serology to CMV before transplantation. During the study period, 3 patients developed asymptomatic CMV reactivation. One patient developed CMV disease (pneumonia). All of the patients were visually asymptomatic during the study period. Two patients (15%) had a history of diabetes mellitus and chronic severe arterial hypertension. Seven recipients (53%) had been heavy cigarette smokers and 3 patients (23%) had hyperlipidemia. Two (15%) of 13 patients with arterial hypertension and diabetes had evidence of asymptomatic active CMV retinitis. These patients were treated with intravenous ganciclovir. Conclusions: Active cytomegalovirus retinitis lesions were found in 2 (15%) of 13 cardiac transplantation patients who had no visual symptoms. We think that the patients with systemic microvascular risk factors such as diabetes, hypertension and smoking should be screened closely for the development of CMV retinitis after cardiac transplantation even if the patients have no visual symptoms. Copyright (C) 2003 S. Karger AG, Basel.en_US
dc.identifier.doi10.1159/000073078en_US
dc.identifier.endpage450en_US
dc.identifier.issn0030-3755
dc.identifier.issue6en_US
dc.identifier.pmid14573981en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage446en_US
dc.identifier.urihttps://doi.org/10.1159/000073078
dc.identifier.urihttps://hdl.handle.net/11454/36571
dc.identifier.volume217en_US
dc.identifier.wosWOS:000186459700013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherKargeren_US
dc.relation.ispartofOphthalmologicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectcytomegalovirus retinitisen_US
dc.subjectcardiac transplantationen_US
dc.titleAsymptomatic cytomegalovirus retinitis after cardiac transplantationen_US
dc.typeArticleen_US

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