Onikomikozda klinik görünüm ve etken ilişkisi
Küçük Resim Yok
Tarih
2008
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Onikomikozun klinik tipleri etken olan ajanlara göre değişiklik gösterebilmektedir. Biz de kliniğimize başvuran ve onikomikoz tanısı alan hastalarda klinik tip ile üreyen etken, yaş ve cins arasındaki ilişkiyi saptamayı amaçladık. Yöntem: Ege Üniversitesi Tıp Fakültesi Dermatoloji Polikliniği’ne başvuran, klinik ve mikolojik olarak onikomikoz tanısı alan 110 hasta araştırmaya alındı. Bulguları distal lateral subungual onikomikoz (DLSO), proksimal subungual onikomikoz (PSO), total distrofik onikomikoz (TDO), yüzeysel beyaz onikomikoz (YBO), kandidal onikomikoz olarak kaydedildi. Tırnaktan alınan kazıntı örneklerinden direkt mikroskobik tetkik ve kültür ekimleri yapıldı. Hastalarda el ve ayak onikomikozu ayrı olarak kaydedildi. Bulgular: Çalışmaya dahil edilen 110 hastanın [48 erkek (%43.6), 62 kadın (56.4%)] yaşları 14-87 (50,61±13.34) arasında idi. Onikomikoz 96 (87.3%) hastada ayak, 14 (12.7%) hastada el tırnağında idi. Onikomikoz klinik tipi hastaların %61.5’ inde DLSO, %28,4’ ünde ise TDO idi. Kültürlerde en sık rastlanan etken, ayak tırnaklarında Trichophyton rubrum (%62.5), el tırnaklarında ise Candida albicans (%71.4) idi. Kültürde üreyen etken ile lokalizasyon ilişkisi istatistiksel olarak anlamlı bulundu (p=0,001). Klinik tipler içinde DLSO’da %61.2 Trichophyton rubrum, %34.3 Candida albicans; TDO’da %54.8 Trichophyton rubrum, %32.3 Candida albicans; YBO’da % 50 Trichophyton rubrum, %33.3 Candida albicans üremesi saptandı. Etken ile klinik tip arasında istatistiksel bir ilişki saptanmadı (p=0,136). Sonuç: Onikomikoz hastalarında en sık saptanan klinik tip DLSO, en sık rastlanan etken ayakta Trichophyton rubrum, elde Candida albicans olmuştur. Etken ile klinik tip arasında istatistiksel olarak anlamlı bir ilişki saptanamamıştır.
Objective: The clinic types of onychomycosis can change according to causative agents. In this study, we aimed to investigate the relationship between clinical type and isolated agent, and the age and sex of onychomycosis patients who admitted to our clinic. Method: 110 patients who admitted to Ege University Medical Faculty, Department of Dermatology with onychomycosis diagnosed on clinical and mycological findings, were included in the study. Nail findings were distal-lateral subungual onychomycosis (DLSO), proximal subungual onychomycosis (PSO), total dystrophic onychomycosis (TDO), white superficial onychomycosis (WSO) and candidal onychomycosis. Direct microscopic examination and cultures were performed with nail scrapings specimens. Toenail and fingernail results were recorded separately. Results: The ages of the 110 patients [(48 male (43.6%), 62 female (56.4%)] who enrolled the study were between 14-87 (50,61±13.34) years. Onychomycosis was localised in toenail in 96 (87.3%) and fingernail in 14 (12.7%) patients. The most frequently seen clinical types of onychomycosis were DLSO (61.5%) and TDO (28,4%). The most common isolated agents were Trichophyton rubrum (62.5%) in toenail and Candida albicans (71.4%) in fingernail. The relationship between isolated agent and localization was statistically significant (p=0,001). In addition Trichophyton rubrum (61.2%) and Candida albicans (34.3%) in DLSO; Trichophyton rubrum (54.8%) and Candida albicans (32.3%) in TDO and, Trichophyton rubrum (50%), Candida albicans (33.3%) in WSO were isolated. There was no relationship between clinical type and isolated agent (p=0,136). Conclusion: The most common clinical type of onychomycosis was found to be DLSO and the most common isolated agent was Trichophyton rubrum in toenail and Candida albicans in fingernail scrapings. There was no relationship between clinical type and isolated agent.
Objective: The clinic types of onychomycosis can change according to causative agents. In this study, we aimed to investigate the relationship between clinical type and isolated agent, and the age and sex of onychomycosis patients who admitted to our clinic. Method: 110 patients who admitted to Ege University Medical Faculty, Department of Dermatology with onychomycosis diagnosed on clinical and mycological findings, were included in the study. Nail findings were distal-lateral subungual onychomycosis (DLSO), proximal subungual onychomycosis (PSO), total dystrophic onychomycosis (TDO), white superficial onychomycosis (WSO) and candidal onychomycosis. Direct microscopic examination and cultures were performed with nail scrapings specimens. Toenail and fingernail results were recorded separately. Results: The ages of the 110 patients [(48 male (43.6%), 62 female (56.4%)] who enrolled the study were between 14-87 (50,61±13.34) years. Onychomycosis was localised in toenail in 96 (87.3%) and fingernail in 14 (12.7%) patients. The most frequently seen clinical types of onychomycosis were DLSO (61.5%) and TDO (28,4%). The most common isolated agents were Trichophyton rubrum (62.5%) in toenail and Candida albicans (71.4%) in fingernail. The relationship between isolated agent and localization was statistically significant (p=0,001). In addition Trichophyton rubrum (61.2%) and Candida albicans (34.3%) in DLSO; Trichophyton rubrum (54.8%) and Candida albicans (32.3%) in TDO and, Trichophyton rubrum (50%), Candida albicans (33.3%) in WSO were isolated. There was no relationship between clinical type and isolated agent (p=0,136). Conclusion: The most common clinical type of onychomycosis was found to be DLSO and the most common isolated agent was Trichophyton rubrum in toenail and Candida albicans in fingernail scrapings. There was no relationship between clinical type and isolated agent.
Açıklama
Anahtar Kelimeler
Dermatoloji
Kaynak
Türk Dermatoloji Dergisi
WoS Q Değeri
Scopus Q Değeri
Cilt
2
Sayı
1
