The Efficacy of Intralesional Steroid Injection in the Treatment of Corrosive Esophageal Strictures in Children
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams & Wilkins
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Purpose of the Study: Esophageal dilatation can be insufficient in the treatment of severe corrosive esophageal strictures. In this study, we aimed to present the efficacy of intralesional steroid injection as an adjunct to dilatation therapy. Materials and Methods: Retrospective analysis of children who underwent intralesional steroid injection between 2004 and 2014 was performed. Patients' age, type of corrosive substance, length of stricture, number of injection and dilatation sessions and complications were reviewed. The success was evaluated by the comparison of number, frequency, and requirement of dilatation therapy before and after injection. Results: Intralesional steroid injection was performed to 32 children with a mean age of 3.6 +/- 2.5 years. The types of corrosive agents were alkali (24) or acid (8). Mean number of injection sessions was 2.5 +/- 1.1(1 to 6). Mean number of dilatation sessions was decreased from 10 +/- 8.8 to 5.4 +/- 4.6 after injection (P= 0.003). Mean frequency of dilatations was extended from 3.6 +/- 0.9 weeks to 8.7 +/- 3.9 weeks (P= 0.000). Dilatation treatment was successfully terminated in 25 of 27 children with short-segment strictures after injection (92%). Whereas all of the children with long-segment strictures could not resolved and finally required esophageal replacement (5 patients). One patient had transient cushingoid phenotype as a complication. There was not seen any major complication-like perforation. The mean follow-up period was 6 +/- 3 years. Conclusions: Intralesional steroid injection is an effective adjunct to dilatation in most of the children with short-segment strictures. It should be performed as a safe and efficient treatment option in patients with short-segment corrosive esophageal strictures resistant to dilatation therapy.
Açıklama
Anahtar Kelimeler
intralesional steroid injection, corrosive esophageal stricture, caustic stricture, esophageal dilatation, children
Kaynak
Surgical Laparoscopy Endoscopy & Percutaneous Techniques
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
26
Sayı
6
