Distribution of fibronectin, laminin and collagen type IV in the materno-fetal boundary zone of the developing mouse placenta: Experimental study

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dc.contributor.authorSaylam C.
dc.contributor.authorÖzdemir N.
dc.contributor.authorItil I.M.
dc.contributor.authorSendag F.
dc.contributor.authorTerek M.C.
dc.date.accessioned2019-10-27T00:24:02Z
dc.date.available2019-10-27T00:24:02Z
dc.date.issued2002
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: The objective of this study is to demonstrate the distribution of extracellular matrix components of fibronectin, laminin and collagen type IV in the materno-fetal boundary zone of the developing mouse placenta. Material and methods: Mice fetuses and placentas were removed serially every day until the 19th gestational day. Implantation sites were processed and stained by an immunohistochemical method by specific antiserums to fibronectin, laminin and collagen type IV. The distribution of the extracellular matrix components in cytotrophoblasts and giant cells of the developing mouse placenta were determined under light microscope. Results: Fibronectin, laminin and collagen type IV immunostaining demonstrated a dynamic relationship changing day by day after the conception. At the 16th day cytotrophoblasts and giant cells were all positively stained by the extracellular matrix components. Conclusion: This study demonstrates that the regions of the developing mouse placenta produce specialized extracellular matrices which may contain different ratios of these polypeptides.en_US
dc.identifier.doi10.1007/s004040100204en_US
dc.identifier.endpage85en_US
dc.identifier.issn0932-0067
dc.identifier.issue2en_US
dc.identifier.pmid12049301en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage83en_US
dc.identifier.urihttps://doi.org/10.1007/s004040100204
dc.identifier.urihttps://hdl.handle.net/11454/22972
dc.identifier.volume266en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofArchives of Gynecology and Obstetricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCollagen type IVen_US
dc.subjectFibronectinen_US
dc.subjectLamininen_US
dc.subjectMouse placentaen_US
dc.titleDistribution of fibronectin, laminin and collagen type IV in the materno-fetal boundary zone of the developing mouse placenta: Experimental studyen_US
dc.typeArticleen_US

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