Cognıtıve functıons in idiopathic intracranial hypertensıon

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dc.contributor.authorAk, Aysin Kisabay
dc.contributor.authorSaritas, Aysegul Seyma
dc.contributor.authorBatum, Melike
dc.contributor.authorGemici, Yagmur Inalkac
dc.contributor.authorKarakas, Burak
dc.contributor.authorCelebisoy, Nese
dc.date.accessioned2024-08-31T07:50:58Z
dc.date.available2024-08-31T07:50:58Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectiveCognitive problems in idiopathic intracranial hypertension (IIH) is generally overlooked in the presence of disabling headache and threat to visual function. The aim of this study was to search for cognitive deficits in patients with IIH using neuropsychologic tests in addition to P300 potential recordings to assess cognition related brain activity.MethodsFifty IIH patients were examined using Montreal Cognitive Assessment Test, Stroop Test and Visual Aural Digit Span Test to measure different domains of cognition at the time of diagnosis. P300 potentials were recorded by using an oddball paradigm. Hospital Anxiety and Depression Scale was used to determine anxiety and depression. Quality of life (QoL) was assessed by SF-36. The results were compared with fifty healthy controls with matching age, gender and body mass index.ResultsNeuropsychologic tests revealed wide cognitive impairment including attention, working memory, executive function, naming, language, delayed recall and orientation in IIH patients. In addition, quality of life was affected in the sub-parameters of general health perceptions, emotional role functioning, vitality, mental health and bodily pain. P300 potential latencies were long and the amplitudes were reduced indicating deficits in attention and working memory. Anxiety scores were high, and health-related QoL was low mainly involving vitality, emotional and mental health. Cognitive dysfunction was not correlated with the levels of anxiety and the correlation with headache severity was mild.ConclusionA multidomain cognitive decline mainly involving attention and working memory was recorded in IIH patients. It was not correlated with anxiety and only a mild correlation with headache severity was present which may indicate a casual relationship between raised intracranial pressure and cognitive deficits. Screening is important as neuropsychological rehabilitation might be relevant in these patients.en_US
dc.identifier.doi10.1007/s13760-024-02550-9
dc.identifier.issn0300-9009
dc.identifier.issn2240-2993
dc.identifier.pmid38709464en_US
dc.identifier.scopus2-s2.0-85192189911en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1007/s13760-024-02550-9
dc.identifier.urihttps://hdl.handle.net/11454/105448
dc.identifier.wosWOS:001214857400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofActa Neurologica Belgicaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240831_Uen_US
dc.subjectIdiopathic Intracranial Hypertensionen_US
dc.subjectCognitionen_US
dc.subjectNeuropsychologic Testsen_US
dc.subjectP300en_US
dc.titleCognıtıve functıons in idiopathic intracranial hypertensıonen_US
dc.typeArticleen_US

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