Data on prevalence of dyslipidemia and lipid values in Turkey: Systematic review and meta-analysis of epidemiological studies on cardiovascular risk factors

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dc.contributor.authorKayikcioglu, Meral
dc.contributor.authorTokgozoglu, Lale
dc.contributor.authorKilickap, Mustafa
dc.contributor.authorGoksuluk, Huseyin
dc.contributor.authorKaraaslan, Doruk
dc.contributor.authorOzer, Necla
dc.contributor.authorAbaci, Adnan
dc.contributor.authorYilmaz, Mehmet Birhan
dc.contributor.authorBarcin, Cem
dc.contributor.authorAtes, Kenan
dc.contributor.authorBayram, Fahri
dc.contributor.authorSahin, Mahmut
dc.contributor.authorUral, Dilek
dc.date.accessioned2019-10-27T10:01:35Z
dc.date.available2019-10-27T10:01:35Z
dc.date.issued2018
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective: Dyslipidemias, primarily hypercholesterolemia, are independent and strong predictors of cardiovascular (CV) events. The frequency of dyslipidemia is very important in terms of determining CV prevention policies. In order to determine the up-to-date frequency of CV risk factors in Turkey, a meta-analysis of the epidemiologic studies carried out in the last 15 years was performed. This article presents the results on the dyslipidemia data including hypercholesterolemia principally. Methods: Epidemiological studies conducted during the last 15 years and having the potential to represent the general population in Turkey were searched in databases (Ovid Medline, Web of Science Core Collection, and Turkish Academic Network and Information Center [ULAKBIM]) and web pages (Ministry of Health, Turkey Statistical Institute, Turkish Society of Cardiology, Nephrology and Endocrinology Associations). A total of 7 studies including lipid data were found. Systematic review and meta-analysis of the studies with low bias score were performed. Crude values of the prevalence of hypercholeterolemia, hypertriglyceridemia and low HDL and mean lipid levels were calculated. Random effects model was used in meta-analysis. Results: The prevalence of hypercholesterolemia defined as a LDL-cholesterol > 130 and/or >= 130 mg/dL, was 29.1% (95% CI 23.6-35.0) in the general population, 30.2% in females (%95 CI 24.7-36.1), and 27.8% in males (95% CI 22.3-33.6). The prevalence of low HDL-cholesterol (<= 50 mg/dL for females and <= 40 mg/dL for males) was calculated as 46.1% (95% CI 42.4-49.9) in the whole group, 50.7% (95% CI 47.7-53.6) in females and 41.1% (95% CI 36.1-46.3) in males. The prevalence of hypertriglyceridemia (> 150 mg/dL) was 36.5% (95% CI 30.6-42.5) in general, 32.0% (95% GA 26.6-37.8) in females and 41.3% (95% CI 34.9-47.8) in males. Conclusion: Dyslipidemia constitutes a major public health problem in Turkey. In the adult population, almost 3 of 10 have hypercholesterolemia, one of 2 has a low HDL-cholesterol, and 1 of 3 has high triglycerides levels.en_US
dc.identifier.doi10.5543/tkda.2018.23450en_US
dc.identifier.endpage574en_US
dc.identifier.issn1016-5169
dc.identifier.issue7en_US
dc.identifier.pmid30391985en_US
dc.identifier.startpage556en_US
dc.identifier.urihttps://doi.org/10.5543/tkda.2018.23450
dc.identifier.urihttps://hdl.handle.net/11454/29871
dc.identifier.volume46en_US
dc.identifier.wosWOS:000453084600006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isotren_US
dc.publisherTurkish Soc Cardiologyen_US
dc.relation.ispartofTurk Kardiyoloji Dernegi Arsivi-Archives of the Turkish Society of Cardiologyen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectEpidemiologyen_US
dc.subjectHypercholesterolemiaen_US
dc.subjecthypertriglyceridemiaen_US
dc.subjectmeta-analysisen_US
dc.subjectprevalenceen_US
dc.subjectTurkeyen_US
dc.titleData on prevalence of dyslipidemia and lipid values in Turkey: Systematic review and meta-analysis of epidemiological studies on cardiovascular risk factorsen_US
dc.typeReview Articleen_US

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