Effects of coasting on the outcome of intracytoplasmic sperm injection-embryo transfer cycles

Küçük Resim Yok

Tarih

2004

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Objectives: To determine the effects of 'coasting' on the outcome of controlled ovarian hyperstimulation (COH) and intracytoplasmic sperm injection-embryo transfer (ICSI-ET). Design: Retrospective study. Setting: IVF Centre, Ozel Ege Tup Bebek Merkezi, Izmir, Turkey. Sample: Twenty-six coasted and 52 non-coasted COH and ICSI-ET patients were enrolled in this retrospective study. Methods: Coasted patients were enrolled consecutively during the study period, and two non-coasted controls were selected from our database for each coasted patient. Coasting was decided when serum oestradiol level was ?4000 pg/mL. Groups were compared using x2 and Mann-Whitney U-tests for statistical analysis. Main Outcome Measures: Number of oocytes collected, metaphase II (MII) oocytes and cleaving embryos, the fertilisation rate and clinical pregnancy rate were the main outcome measures. Results: Number of oocytes collected, number of MII oocytes, number of cleaving embryos, fertilisation rate and clinical pregnancy rate for the coasted and non-coasted groups were 15.5 ± 5.2 and 14.0 ± 7.1, 9.7 ± 4.8 and 9.3 ± 3.9, 6.8 ± 3.9 and 5.8 ± 3.1, 0.85 ± 0.18 and 0.78 ± 0.18, 13/26 and 24/52, respectively; these differences were not statistically significant. None of the patients in the coasted group were hospitalised for signs or findings of severe ovarian hyperstimulation syndrome. Conclusions: Coasting does not adversely affect the number and the function of mature oocytes and the clinical pregnancy rate.

Açıklama

Anahtar Kelimeler

Coasting, Intracytoplasmic sperm injection, Outcome, Ovarian hyperstimulation syndrome

Kaynak

Australian and New Zealand Journal of Obstetrics and Gynaecology

WoS Q Değeri

Scopus Q Değeri

N/A

Cilt

44

Sayı

4

Künye