Diagnostic accuracy of the mean platelet volume in the prediction of upper urinary tract infections
Küçük Resim Yok
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Verlag Klinisches Labor GmbH
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Background: The studies have reported that mean platelet volume may be a marker in the discrimination of upper and lower urinary tract infections. We investigated whether the mean platelet volume was a reliable indicator in upper and lower urinary tract infections. Methods: One hundred and eighty-two patients between the ages of 1 month and 14 years who were diagnosed with urinary tract infection were included in this study. The mean platelet volume values, clinical and other laboratory characteristics of the groups were compared. The discriminative ability of each biomarker for patients with UUTI was evaluated by drawing receiver operating characteristic (ROC) curves for the biomarkers. All values of p < 0.05 were considered statistically significant. Results: The leukocyte count, C-reactive protein, and erythrocyte sedimentation rates of the patients with upper urinary tract infection were significantly higher than the patients with lower urinary tract infections (p < 0.001). However, there was no statistically significant difference in terms of the mean platelet volume values between patients with upper and lower urinary tract infection ([7.2 (1.3) vs. 7.2 (1.6) fL]; p = 0.79, respectively). The value of the area under the curve of MPV's p-value was > 0.05. However, p-values of CRP and ESR were significant in ROC analysis. Conclusions: Our study showed that there was no significant difference in the mean platelet volume values between patients with upper and lower urinary tract infections. The use of mean platelet volume as an indicator of upper urinary tract infection is controversial. © 2020 Verlag Klinisches Labor GmbH. All rights reserved.
Açıklama
Anahtar Kelimeler
Child, Inflammation, Lower urinary tract infection, Mean platelet volume, Upper urinary tract infection, biological marker, C reactive protein, adolescent, Article, child, diagnostic accuracy, diagnostic test accuracy study, erythrocyte sedimentation rate, Escherichia coli infection, female, hospitalized child, human, laboratory test, leukocyte count, major clinical study, male, mean platelet volume, nonhuman, pediatric patient, prediction, receiver operating characteristic, sensitivity and specificity, urinary tract infection, urine culture, blood, classification, hospitalization, infant, preschool child, urinary tract infection, Adolescent, Child, Child, Preschool, Female, Hospitalization, Humans, Infant, Male, Mean Platelet Volume, ROC Curve, Urinary Tract Infections
Kaynak
Clinical Laboratory
WoS Q Değeri
Scopus Q Değeri
Q3
Cilt
66
Sayı
3
