Helicobacter pylori infection in children with celiac disease

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dc.contributor.authorAydogdu, Sema
dc.contributor.authorCakir, Murat
dc.contributor.authorYuksekkaya, Hasan Ali
dc.contributor.authorTumgor, Gokhan
dc.contributor.authorBaran, Masallah
dc.contributor.authorArikan, Cigdem
dc.contributor.authorYagci, Rasit V.
dc.date.accessioned2019-10-27T19:57:53Z
dc.date.available2019-10-27T19:57:53Z
dc.date.issued2008
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective. To analyze the prevalence of Helicobacter pylori (H. pylori) infection in children with celiac disease (CD) and to examine the role of H. pylori infection in clinical, laboratory and histopathological presentations of CD. Material and methods. Data on 96 children with CD and 235 children who underwent endoscopy were compared for the prevalence and gastric histology pattern of H. pylori. Clinical presentation, laboratory and histological findings of CD children with and without H. pylori infection were compared. Results. Twenty-one subjects (21.8%) in the CD group and 56 subjects (23.8%) in the control group had H. pylori gastritis. Gastric metaplasia is higher in CD patients with H. pylori gastritis (19%) than in patients without H. pylori gastritis (1.3%) and in the control group (3.5%) (p0.05 for all groups). Abdominal distension is more common at initial admission in CD patients with H. pylori gastritis (57.1% versus 14.6%, p0.05). No significant difference was found between H. pylori (+) and (-) CD patients in terms of prevalence of anemia, iron deficiency and iron-deficiency anemia. Only mild duodenal histological findings were more common in H. pylori patients (57.1% versus 26.7%, p < 0.05). Conclusions. CD may be associated with H. pylori gastritis, but it does not affect the clinical presentation of the disease, except for abdominal distension; CD is associated with mild duodenal lesions. A gluten-free diet improves the symptoms in all patients independently of the presence of H. pylori gastritis. Gastric metaplasia increases in the presence of H. pylori gastritis. Further prospective studies are needed to examine the clinical and histopathological outcomes of gastric metaplasia associated with H. pylori gastritis in CD patients.en_US
dc.identifier.doi10.1080/00365520802101846en_US
dc.identifier.endpage1093en_US
dc.identifier.issn0036-5521
dc.identifier.issn1502-7708
dc.identifier.issue9en_US
dc.identifier.pmid18609161en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1088en_US
dc.identifier.urihttps://doi.org/10.1080/00365520802101846
dc.identifier.urihttps://hdl.handle.net/11454/41007
dc.identifier.volume43en_US
dc.identifier.wosWOS:000258589500010en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofScandinavian Journal of Gastroenterologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectceliac diseaseen_US
dc.subjectgastric metaplasiaen_US
dc.subjectHelicobacter pylorien_US
dc.subjectiron-deficiency anemiaen_US
dc.titleHelicobacter pylori infection in children with celiac diseaseen_US
dc.typeArticleen_US

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