Isolation of resveratrol from peanut sprouts, radioiodination and investigation of its bioactivity on neuroblastoma cell lines
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Recently, natural antioxidant substances have been purified in a significant increasing incline from different plants for diagnosis and treatment options. in the current study, Resveratrol (RES) was isolated and radioiodinated with iodine-131 ([I-131]iodo-RES). Cell culture studies were conducted on neuroblastoma cells (SY-SH5Y and SK-N-AS) to investigate the bioavailability of [I-131]iodo-RES. the radioiodination yield of RES was 98.81 +/- 0.37% (n = 6). Uptake values up to 25% were observed notably on SK-N-AS cells until 24 h. Briefly; the current study will contribute to the development of novel radiolabeled plant origin agents for the imaging of neuroblastoma cells.
Açıklama
Anahtar Kelimeler
Peanut sprouts, Resveratrol, Iodine-131, Radioiodination, Human neuroblastoma cell lines
Kaynak
Journal of Radioanalytical and Nuclear Chemistry
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
325
Sayı
1
