Brain natriuretic peptide: the reason of respiratory distress is heart disease or lung disease?

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dc.contributor.authorSahingozlu, Taylan
dc.contributor.authorKaradas, Ulas
dc.contributor.authorEliacik, Kayi
dc.contributor.authorBakiler, Ali Rahmi
dc.contributor.authorKaradas, Nihal Ozdemir
dc.contributor.authorKanik, Muhammed Ali
dc.contributor.authorBaran, Masaallah
dc.date.accessioned2019-10-27T20:26:03Z
dc.date.available2019-10-27T20:26:03Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: The aim of this study was to determine whether plasma levels of amino-terminal brain natriuretic peptide (BNP) could differentiate between heart failure and lung disease among infants with acute bronchiolitis. Methods: Sixty-eight infants (age range, 1-26 months; median age, 5.9 +/- 5.0 months) who presented with respiratory distress underwent physical examination, plasma BNP measurement, and echocardiography within 24 hours after admission. Nineteen (28%) patients had congenital heart disease. The control group was consisted of 30 healthy infants. Results: Although mean plasma BNP levels were 118.9 +/- 219.5 pg/mL in patients with isolated bronchiolitis (n = 49), it was 841.2 +/- 1475.8 pg/mL in patients with congenital heart disease (n = 19). Plasma BNP levels were significantly higher in infants with congenital heart disease (P = .001). Conclusion: It was shown that plasma BNP levels were affected much more in cardiac disease rather than lung disease. Among infants with respiratory distress, plasma BNP measurements can differentiate congenital heart disease and lung disease and can be used to monitor the effects of treatment for infants with heart failure. Response to reviewers: The comments were taken for consideration. The patient groups control BNP levels were attached to the results. As it was a clinical study and multiple factors (respiratory score, respiratory rate, treatment, etc) may effect on BNP levels, the tables could not be decreased to 1 table. (C) 2015 Elsevier Inc. All rights reserved.en_US
dc.identifier.doi10.1016/j.ajem.2015.02.005en_US
dc.identifier.endpage700en_US
dc.identifier.issn0735-6757
dc.identifier.issn1532-8171
dc.identifier.issue5en_US
dc.identifier.pmid25704187en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage697en_US
dc.identifier.urihttps://doi.org/10.1016/j.ajem.2015.02.005
dc.identifier.urihttps://hdl.handle.net/11454/42291
dc.identifier.volume33en_US
dc.identifier.wosWOS:000354291600020en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherW B Saunders Co-Elsevier Incen_US
dc.relation.ispartofAmerican Journal of Emergency Medicineen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleBrain natriuretic peptide: the reason of respiratory distress is heart disease or lung disease?en_US
dc.typeArticleen_US

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