Preemptive meloxicam for postoperative pain relief after abdominal hysterectomy
Küçük Resim Yok
Tarih
2004
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: This study was conducted to evaluate the analgesic efficacy of meloxicam in abdominal hysterectomy. Methods: The study population consisted of 52 patients scheduled for total abdominal hysterectomy who were ASA 1 or 2 physical status female. Patients were allocated randomly to receive orally either 15 mg of meloxicam (Group M, n = 27) or placebo (Group P, n = 25) before anesthesia induction. After intravenous administration of 1.5 mg kg-1 of tramadol, anesthesia was induced with an intravenous loading dose of 1-2 mg kg-1 propofol. Anesthesia was maintained on intravenous infusion of propofol at 6-12 mg kg-1 h-1 plus tramadol at 1 mg kg -1 h-1, vecuronium, and a 2:1 nitrous oxide-oxygen mixture. Results: The relative propofol consumption was lower in Group M than in Group P, (p < 0.05). The time for analgesic rescue decreased in the order Group M > Group P (p < 0.01). The degree of sedation was similar between the groups (p > 0.05) and the visual analog scores (10-cm scale) and verbal rating scale data differences were present in the first 2 h only (p < 0.05). When side-effects were evaluated nausea and vomiting were found to be lower in group M than in group P (p < 0.05). Conclusion: Preemptive meloxicam provided better postoperative analgesia than placebo.
Açıklama
Anahtar Kelimeler
Abdominal hysterectomy, Meloxicam
Kaynak
Clinical and Experimental Obstetrics and Gynecology
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
31
Sayı
2
