Detection of Heat Shock Protein (DnaK, DnaJ and GrpE) Horizontal Gene Transfers Among Acanthamoeba polyphaga, Acanthamoeba Polyphaga Mimivirus (APMV), Amoeba-Infecting Bacteria and Sputnik Virophage

dc.contributor.authorHaghi, Morteza
dc.contributor.authorKoseoglu, Ahmet Efe
dc.contributor.authorKaraboz, Ismail
dc.contributor.authorUn, Cemal
dc.date.accessioned2019-10-27T23:12:05Z
dc.date.available2019-10-27T23:12:05Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractAcanthamoeba polyphaga mimivirus (APMV) was isolated in 1992.. It's large size, gram positivity and unique genome features attracted many scientists attention in evolutinary and clinical terms since it's discovery. APMV shares its A. polyphaga host environment with other intracellular bacteria including Campylobacter jejuni, Vibrio cholerae, Legionella pneumophila, Listeria monocytogenes. It has been known that the giant viruses have adopted cellular genes during evolutionary process via horizontal gene transfer (HGT) from bacteria and their eukaryotic host. In this study we aim to detect bacterial Heat shock protein (Dnak, DnaJ and GrpE) genes which are a group of evolutionary conserved proteins that are produced by cellular organisms under stress conditions. As a result of BLAST, significant matches have been found between APMV genome and bacterial genome. Therefore, our results support the adoption of Hsp genes via HGT from bacteria. However, any significant match was not found among APMV, A. polyphaga and Sputnik virophage.en_US
dc.identifier.endpage1622en_US
dc.identifier.issn0976-2612
dc.identifier.issn2278-599X
dc.identifier.issn0976-2612en_US
dc.identifier.issn2278-599Xen_US
dc.identifier.issue4en_US
dc.identifier.startpage1618en_US
dc.identifier.urihttps://hdl.handle.net/11454/53169
dc.identifier.volume7en_US
dc.identifier.wosWOS:000404030100001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherBioit Internationaljournalsen_US
dc.relation.ispartofInternational Journal of Advanced Biotechnology and Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectA. polyphagaen_US
dc.subjectAPMVen_US
dc.subjectSputnik virophageen_US
dc.subjectHeat shock proteinen_US
dc.subjectHorizontal gene transferen_US
dc.subjectBLASTen_US
dc.titleDetection of Heat Shock Protein (DnaK, DnaJ and GrpE) Horizontal Gene Transfers Among Acanthamoeba polyphaga, Acanthamoeba Polyphaga Mimivirus (APMV), Amoeba-Infecting Bacteria and Sputnik Virophageen_US
dc.typeArticleen_US

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