Detection of Heat Shock Protein (DnaK, DnaJ and GrpE) Horizontal Gene Transfers Among Acanthamoeba polyphaga, Acanthamoeba Polyphaga Mimivirus (APMV), Amoeba-Infecting Bacteria and Sputnik Virophage
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Bioit Internationaljournals
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Acanthamoeba polyphaga mimivirus (APMV) was isolated in 1992.. It's large size, gram positivity and unique genome features attracted many scientists attention in evolutinary and clinical terms since it's discovery. APMV shares its A. polyphaga host environment with other intracellular bacteria including Campylobacter jejuni, Vibrio cholerae, Legionella pneumophila, Listeria monocytogenes. It has been known that the giant viruses have adopted cellular genes during evolutionary process via horizontal gene transfer (HGT) from bacteria and their eukaryotic host. In this study we aim to detect bacterial Heat shock protein (Dnak, DnaJ and GrpE) genes which are a group of evolutionary conserved proteins that are produced by cellular organisms under stress conditions. As a result of BLAST, significant matches have been found between APMV genome and bacterial genome. Therefore, our results support the adoption of Hsp genes via HGT from bacteria. However, any significant match was not found among APMV, A. polyphaga and Sputnik virophage.
Açıklama
Anahtar Kelimeler
A. polyphaga, APMV, Sputnik virophage, Heat shock protein, Horizontal gene transfer, BLAST
Kaynak
International Journal of Advanced Biotechnology and Research
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
7
Sayı
4