Multiwalled Carbon Nanotubes-Chitosan Modified Single-Use Biosensors for Electrochemical Monitoring of Drug-DNA Interactions

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dc.contributor.authorSengiz C.
dc.contributor.authorCongur G.
dc.contributor.authorEksin E.
dc.contributor.authorErdem A.
dc.date.accessioned2019-10-26T21:24:03Z
dc.date.available2019-10-26T21:24:03Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstractA multiwalled carbon nanotubes (CNT)-chitosan (CHIT) modified pencil graphite electrode (CNT-CHIT/PGE) was developed for the first time herein for electrochemical monitoring of the interaction of an anticancer drug, mitomycin C (MC) and DNA. The characterization of unmodified PGE, CHIT/PGE, CNT/PGE and CHIT-CNT/PGE were performed by scanning electron microscopy and cyclic voltammetry techniques. The oxidation signals of MC and guanine were measured before and after interaction at the surface of CNT-CHIT/PGEs using differential pulse voltammetry. Electrochemical impedance spectroscopy technique was also successfully utilized for monitoring of the interaction process at the surface of CNT-CHIT/PGEs in different interaction times. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.en_US
dc.identifier.doi10.1002/elan.201500107
dc.identifier.endpage1863en_US
dc.identifier.issn1040-0397
dc.identifier.issn1040-0397en_US
dc.identifier.issue8en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage1855en_US
dc.identifier.urihttps://doi.org/10.1002/elan.201500107
dc.identifier.urihttps://hdl.handle.net/11454/17129
dc.identifier.volume27en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWiley-VCH Verlagen_US
dc.relation.ispartofElectroanalysisen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectChitosanen_US
dc.subjectDrug-DNA interactionsen_US
dc.subjectElectrochemical biosensorsen_US
dc.subjectMitomycin Cen_US
dc.subjectMultiwalled carbon nanotubesen_US
dc.titleMultiwalled Carbon Nanotubes-Chitosan Modified Single-Use Biosensors for Electrochemical Monitoring of Drug-DNA Interactionsen_US
dc.typeArticleen_US

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