High C-Reactive Protein and Low Albumin Levels Predict High 30-Day Mortality in Patients Undergoing Percutaneous Endoscopic Gastrotomy

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dc.contributor.authorKarasahin, Omer
dc.contributor.authorTasar, Pinar Tosun
dc.contributor.authorTimur, Ozge
dc.contributor.authorBinici, Dogan Nasir
dc.contributor.authorYilmaz, Tugba Kiper
dc.contributor.authorAslan, Adem
dc.contributor.authorSahin, Sevnaz
dc.date.accessioned2019-10-27T11:07:34Z
dc.date.available2019-10-27T11:07:34Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Percutaneous endoscopic gastrotomy (PEG) enables long-term enteral feeding. The aim of this study was to identify biomarkers that may guide the decision of whether to perform the elective procedure of PEG. Methods: The medical records of all patients who underwent PEG in our hospital from 2010 to 2016 were screened retrospectively. Patients with mortality within a 30-day follow-up period and those without were compared using the Chi-square test, and continuous variables were compared with the Kruskal-Wallis and Mann-Whitney U tests. Receiver operating characteristic (ROC) curve analysis was used to demonstrate the ability of biomarkers to predict mortality; a cut-off point was determined and its sensitivity, specificity, and positive and negative predictive values were calculated. The Youden index was used to determine the cut-off point. Kaplan-Meier analysis was used to identify PEG-related mortality risk factors and a Cox regression model was applied for risk characterization. Results: A total of 120 patients who underwent PEG were evaluated in the study. The mean age was 67.00 +/- 18.00 years. The most common indication for PEG was cerebrovascular disease, in 69 (57.5%) of the patients. Infection of the PEG site was most common within 14 days after PEG tube placement, occurring in 13 patients (10.3%). The mortality rate among patients with post-PEG infection was 68.2%, significantly higher than in patients without infection (P = 0.012). Thirty-four patients (28.3%) died within 30 days of undergoing PEG. CRP values >= 78.31 mg/ L increased mortality by 8.756-fold, and albumin levels < 2.71 g/dL increased mortality by 2.255-fold. Conclusion: Our results indicate that the presence of both high CRP level and low albumin level were associated with significantly higher rate of mortality (73.1%) in patients who underwent PEG.en_US
dc.identifier.doi10.14740/gr862wen_US
dc.identifier.endpage176en_US
dc.identifier.issn1918-2805
dc.identifier.issn1918-2813
dc.identifier.issue3en_US
dc.identifier.pmid28725304en_US
dc.identifier.startpage172en_US
dc.identifier.urihttps://doi.org/10.14740/gr862w
dc.identifier.urihttps://hdl.handle.net/11454/32049
dc.identifier.volume10en_US
dc.identifier.wosWOS:000406453100004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElmer Press Incen_US
dc.relation.ispartofGastroenterology Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectMortalityen_US
dc.subjectPEGen_US
dc.titleHigh C-Reactive Protein and Low Albumin Levels Predict High 30-Day Mortality in Patients Undergoing Percutaneous Endoscopic Gastrotomyen_US
dc.typeArticleen_US

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