Clinical Characteristics of Obstructive Sleep Apnea Syndrome in Heart Transplant Recipients

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dc.contributor.authorAyik, S.
dc.contributor.authorGungor, H.
dc.contributor.authorAyik, M. F.
dc.contributor.authorEngin, C.
dc.contributor.authorYagdi, T.
dc.contributor.authorNalbantgil, S.
dc.contributor.authorAkhan, G.
dc.contributor.authorOzberan, M.
dc.date.accessioned2019-10-27T21:55:01Z
dc.date.available2019-10-27T21:55:01Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractAim. We investigated the prevalence and clinical characteristics of obstructive sleep apnea syndrome (OSAS) among heart transplantation patients. Methods. Among 86 surviving patients of mean age 43.07 +/- 13.23 years including 35 men transplanted from April 1999 to November 2010, 43 (50%) agreed to participate in this study. Patients with apnea-hypopnea index (AHI) < 5 were labeled as "normal", with an AHI > 5, as obstructive surgeon (OSA). According to the ART, subjects were classified as with OSA (group 1; n = 25 of mean age 49.0 +/- 12.1 years and including 21 men versus non OSA group 2; n = 18) of mean age 34.8 +/- 10.1 years with 14 men. We recorded patient demographic features, medications, polysomnographi observations, laboratory measurements, as well as echocardiographic and angiographic parameters. Results. Prevalence of OSA (AHI > 5) was 58% (n = 25) with 30% (n = 14) as moderate or severe OSA (AHI > 15) OSA patients were significantly older, and showed a greater value of body mass index (BMI) and waist circumference. Echocardiographic findings revealed the only significant difference to be systolic arterial pressure. The apnea-hypopnea index showed significant correlation with age, BMI, waist circumference, neck circumference, Epworth score, duration of apnea episode, time of SaO(2) under 90% and systolic arterial pressure (SPAP). An inverse correlation was observed between ART and sleep efficiency, oxygen saturation, and percentage of time in random eye movement (REM) sleep. Multivariate backward logistic regression analysis indicated waist circumference, sleep efficiency, percentage of time in REM sleeps and duration of apnea episode to be independent predictors of AHI. Conclusion. OSA is prevalent among heart transplantation patients. Obesity is a risk factor and waist circumference, and independent predictor for OSA.en_US
dc.identifier.doi10.1016/j.transproceed.2012.06.076en_US
dc.identifier.endpage386en_US
dc.identifier.issn0041-1345
dc.identifier.issue1en_US
dc.identifier.pmid23375325en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage383en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2012.06.076
dc.identifier.urihttps://hdl.handle.net/11454/48170
dc.identifier.volume45en_US
dc.identifier.wosWOS:000315007200076en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleClinical Characteristics of Obstructive Sleep Apnea Syndrome in Heart Transplant Recipientsen_US
dc.typeArticleen_US

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