Effects of exercise and poor indoor air quality on learning, memory and blood IGF-1 in adolescent mice

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dc.contributor.authorUysal, N.
dc.contributor.authorKiray, M.
dc.contributor.authorSisman, A. R.
dc.contributor.authorBaykara, B.
dc.contributor.authorAksu, I.
dc.contributor.authorDayi, A.
dc.contributor.authorGencoglu, C.
dc.contributor.authorEvren, M.
dc.contributor.authorBuyuk, E.
dc.contributor.authorCetin, F.
dc.contributor.authorAcikgoz, O.
dc.date.accessioned2019-10-27T22:05:23Z
dc.date.available2019-10-27T22:05:23Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractIt is known that regular aerobic exercise enhances cognitive functions and increases blood insulin-like growth factor 1 (IGF-1) levels. People living in urban areas spend most of their time indoors and indoor air quality can affect health. We investigated the effects of aerobic exercise in poor and good air quality environments on hippocampus and prefrontal cortex (PFC) neurons, anxiety, and spatial learning and memory in adolescent mice. Poor air quality impaired spatial learning and memory; exercise did not affect learning or memory impairment. Exercise in a good air quality environment improved spatial learning and memory. Poor air quality increased apoptosis in the hippocampus and PFC. Both exercised and sedentary groups living in a poor air quality environment had lower serum IGF-1 levels than those living in a good air quality environment. Living in a poor air quality environment has negative effects on the hippocampus, PFC and blood IGF-1 levels in adolescent mice, but exercise did not alter the negative effects of poor air quality.en_US
dc.identifier.doi10.3109/10520295.2013.825318en_US
dc.identifier.endpage135en_US
dc.identifier.issn1052-0295
dc.identifier.issn1473-7760
dc.identifier.issue2en_US
dc.identifier.pmid24050191en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage126en_US
dc.identifier.urihttps://doi.org/10.3109/10520295.2013.825318
dc.identifier.urihttps://hdl.handle.net/11454/48397
dc.identifier.volume89en_US
dc.identifier.wosWOS:000329846700008en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherInforma Healthcareen_US
dc.relation.ispartofBiotechnic & Histochemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectadolescenten_US
dc.subjectair qualityen_US
dc.subjectcarbon dioxideen_US
dc.subjectexerciseen_US
dc.subjecthippocampusen_US
dc.subjectIGF-1en_US
dc.subjectlearningen_US
dc.subjectmemoryen_US
dc.subjectprefrontal cortexen_US
dc.titleEffects of exercise and poor indoor air quality on learning, memory and blood IGF-1 in adolescent miceen_US
dc.typeArticleen_US

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