Comparison of remineralization ability of tricalcium silicate and of glass ionomer cement on residual dentin: an in vitro study

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dc.authoridKuru, Elif Hasibe/0000-0002-0396-7677
dc.contributor.authorKuru, Elif
dc.contributor.authorEronat, Nesrin
dc.contributor.authorTurkun, Murat
dc.contributor.authorCogulu, Dilsah
dc.date.accessioned2024-08-31T07:47:19Z
dc.date.available2024-08-31T07:47:19Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractObjective This study aimed to compare the remineralization effects of a calcium silicate-based cement (Biodentine) and of a glass ionomer cement (GIC: Fuji IX) on artificially demineralized dentin. Methods Four standard cavities were prepared in dentin discs prepared from 34 extracted sound human third molars. In each disc, one cavity was covered with an acid-resistant varnish before demineralization (Group 1). The specimens were soaked in a chemical demineralization solution for 96 h to induce artificial carious lesions. Thereafter, one cavity each was filled with Biodentine (Group 2) and GIC (Group 3), respectively, and one carious lesion was left unrestored as a negative control (Group 4). Next, specimens were immersed in simulated body fluid (SBF) for 21 days. After cross-sectioning the specimens, the Ca/P ratio was calculated in each specimen by using scanning electron microscopy-energy-dispersive X-ray spectroscopy (SEM-EDX). Finally, data were analyzed using repeated-measures ANOVA with post-hoc Bonferroni correction. Results Both cement types induced dentin remineralization as compared to Group 4. The Ca/P ratio was significantly higher in Group 2 than in Group 3 (p < 0.05). Conclusion The dentin lesion remineralization capability of Biodentine is higher than that of GIC, suggesting the usefulness of the former as a bioactive dentin replacement material. Clinical relevance Biodentine has a higher remineralization ability than that of GIC for carious dentin, and its interfacial properties make it a promising bioactive dentin restorative material.en_US
dc.description.sponsorshipEge University Scientific Research Project Grant [20739]en_US
dc.description.sponsorshipThis work was supported by Ege University Scientific Research Project Grant (Grant number: 20739)en_US
dc.identifier.doi10.1186/s12903-024-04475-4
dc.identifier.issn1472-6831
dc.identifier.issue1en_US
dc.identifier.pmid38926776en_US
dc.identifier.scopus2-s2.0-85197151468en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.urihttps://doi.org/10.1186/s12903-024-04475-4
dc.identifier.urihttps://hdl.handle.net/11454/104391
dc.identifier.volume24en_US
dc.identifier.wosWOS:001255491400001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofBmc Oral Healthen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240831_Uen_US
dc.subjectBioactive Dental Materialsen_US
dc.subjectCalcium Silicate Cementen_US
dc.subjectDentin Remineralizationen_US
dc.subjectGlass Ionomer Cementen_US
dc.titleComparison of remineralization ability of tricalcium silicate and of glass ionomer cement on residual dentin: an in vitro studyen_US
dc.typeArticleen_US

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