Kemik ve yumuşak doku tümörlerinin dağılımı
Küçük Resim Yok
Tarih
2011
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Kemik ve yumuşak doku tümörlerinin tanı ve tedavisi için multidisipliner yaklaşım gereklidir. Bu amaçla kurulan Ege Üniversitesi İskelet Sistemi Tümörleri Konseyi, 1989-2009 yılları arasında iskelet sistemi tümörü ön tanısı ile yaklaşık 6,000 hastayı değerlendirmiştir. Çalışmamızda bu hasta grubundan elde edilen demografik verilerin sunulması amaçlanmıştır. Çalışma planı: İskelet sitemi tümörü şüphesi taşıyan 5,658 hasta geriye dönük olarak değerlendirilmiştir. Konseyde birden çok görüşülen hastaların tekrarlayan kayıtları çalışmadan çıkartılmıştır. Bulgular: Toplam 5,658 olgunun %39.7'si habis mezenkimal tümörlü hastalardır. Selim tümörler %17, tümör benzeri lezyonlar %17.8, metastazlar ise %8.6 oranında bulunmuştur. Sarkomların %50.2'si kemik, %49.8'i yumuşak doku kökenlidir. Habis kemik tümörleri içinde osteosarkomlar %33.6, Ewing-PNET %25.5, habis kıkırdak tümörleri %19.4, hematopoetik habasetler ise %17.6 olarak bulunmuştur. Yumuşak doku sarkomları içinde pleomorfik hücreli sarkomlar %24.5, liposarkomlar %16.4, sinovyal sarkom %13, indifferansiye sarkomlar ise %8.8 oranındadır. Selim tümörlerin %48'i yumuşak doku tümörleri, %28'i selim kıkırdak tümörleri, %15'i dev hücreli kemik tümörü ve %9'u osteojenik selim tümörlerdi. Hemanjioma, lipoma, agresif fibromatozis, enkondroma, soliter kondroma ve osteoid osteoma gruplarında en sık görülen selim tümörlerdi. Kemikte görülen tümör benzeri lezyonların %15.9'u anevrizmal kemik kisti, %15.3'ü fibröz displazi ve %5'i basit kemik kisti olarak bulunmuştur. Kemikteki karsinom metastazları içinde akciğer kanser metastazları %27, meme kanser metastazları %24, gastrointestinal kanser metastazları %10.5 ve böbrek kanser metastazları %8.2 oranında görülmüştür. Çıkarımlar: Kemik ve yumuşak doku tümörlerinin tanısal dağılımı konusunda Türkiye de geniş istatistiksel bir çalışma yoktur. Çalışmamızın bu konuya katkı sağlayacağını düşünüyoruz.
Objective: Multidisciplinary approach is a necessity for the appropriate diagnosis and treatment of bone and soft tissue tumors. The Ege University Musculoskeletal Tumor Council offers con- sultation services to other hospitals in the Aegean region. Since 1988 the Council has met week- ly and spent approximately 1,500 hours evaluating almost 6,000 patients with suspected skeletal system tumors. Our objective was to present the data obtained from this patient group. Methods: A total of 5,658 patients, suspected to have a musculoskeletal tumor, were evaluated retrospectively. Multiple records of the patients due to multiple attendance to the Council were excluded. The prevalance of the bone and soft tissue tumors in these patients were analysed. Results: Malignant mesenchymal tumors accounted for 39.7% of the total patients, benign tumors for 17%, tumor-like lesions for 17.8% and metastatic carsinomas for 8.6%. Malignant bone tumors were 50.2% and malignant soft tissue tumors were 49.8% of all the sarcomas. Among the malignant bone tumors the most common was osteosarcomas at a rate of 33.6%, fol- lowed by Ewing-PNET at 25.5%, chondrosarcomas at 19.4% and haematopoietic tumors at 17.6%. Pleomorphic sarcomas (24.5%), liposarcoma (16.4%), synovial sarcoma (13%) and undifferential sarcomas (8.8%) were the most common types of malignant sof tissue tumors. Benign soft tissue tumors (48%), benign cartilage tumors (28%), giant cell tumor (15%) and osteogenic tumors (9%) were found among the benign tumors. Hemangioma, lipoma, agressive fibromatosis, enchondroma, solitary chondroma and osteoid osteoma were the most common tumors in their groups. Lung (27%), breast (24%), gastrointestinal system (10.5%) and kidney (8.2%) carcinomas were the most common primary sites of the bone metastasis. Conclusion: Turkey still lacks a comprehensive series indicating the incidence and diagnostic distribution of bone and soft tissue tumors. The presented data would add to our knowledge on the specific rates of the bone and soft tissue tumors in Aegean region.
Objective: Multidisciplinary approach is a necessity for the appropriate diagnosis and treatment of bone and soft tissue tumors. The Ege University Musculoskeletal Tumor Council offers con- sultation services to other hospitals in the Aegean region. Since 1988 the Council has met week- ly and spent approximately 1,500 hours evaluating almost 6,000 patients with suspected skeletal system tumors. Our objective was to present the data obtained from this patient group. Methods: A total of 5,658 patients, suspected to have a musculoskeletal tumor, were evaluated retrospectively. Multiple records of the patients due to multiple attendance to the Council were excluded. The prevalance of the bone and soft tissue tumors in these patients were analysed. Results: Malignant mesenchymal tumors accounted for 39.7% of the total patients, benign tumors for 17%, tumor-like lesions for 17.8% and metastatic carsinomas for 8.6%. Malignant bone tumors were 50.2% and malignant soft tissue tumors were 49.8% of all the sarcomas. Among the malignant bone tumors the most common was osteosarcomas at a rate of 33.6%, fol- lowed by Ewing-PNET at 25.5%, chondrosarcomas at 19.4% and haematopoietic tumors at 17.6%. Pleomorphic sarcomas (24.5%), liposarcoma (16.4%), synovial sarcoma (13%) and undifferential sarcomas (8.8%) were the most common types of malignant sof tissue tumors. Benign soft tissue tumors (48%), benign cartilage tumors (28%), giant cell tumor (15%) and osteogenic tumors (9%) were found among the benign tumors. Hemangioma, lipoma, agressive fibromatosis, enchondroma, solitary chondroma and osteoid osteoma were the most common tumors in their groups. Lung (27%), breast (24%), gastrointestinal system (10.5%) and kidney (8.2%) carcinomas were the most common primary sites of the bone metastasis. Conclusion: Turkey still lacks a comprehensive series indicating the incidence and diagnostic distribution of bone and soft tissue tumors. The presented data would add to our knowledge on the specific rates of the bone and soft tissue tumors in Aegean region.
Açıklama
Anahtar Kelimeler
Cerrahi
Kaynak
Acta Orthopaedica et Traumatologica Turcica
WoS Q Değeri
Scopus Q Değeri
Cilt
45
Sayı
3
