Longitudinal study of bone loss in chronic spinal cord injury patients

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dc.contributor.authorKarapolat, Inanc
dc.contributor.authorKarapolat, Hale Uzumcugil
dc.contributor.authorKirazli, Yesim
dc.contributor.authorCapaci, Kazim
dc.contributor.authorAkkoc, Yesim
dc.contributor.authorKumanlioglu, Kamil
dc.date.accessioned2019-10-27T20:25:56Z
dc.date.available2019-10-27T20:25:56Z
dc.date.issued2015
dc.departmentEge Üniversitesien_US
dc.description.abstract[Purpose] This prospective longitudinal study evaluated the changes in bone metabolism markers and bone mineral density of spinal cord injury patients over 3 years. We also assessed the relationships among the bone mineral density, bone metabolism, and clinical data of spinal cord injury patients. [Subjects and Methods] We assessed the clinical data (i.e., immobilization due to surgery, neurological status, neurological level, and extent of lesion) in 20 spinal cord injury patients. Bone mineral density, and hormonal and biochemical markers of the patients were measured at 0, 6, 12, and 36 months. [Results] Femoral neck T score decreased significantly at 36 months (p < 0.05). Among the hormonal markers, parathyroid hormone and vitamin D were significantly elevated, while bone turnover markers (i.e., deoxypyridinoline and osteocalcin) were significantly decreased at 12 and 36 months (p < 0.05). [Conclusion] Bone mineral density of the femoral neck decreases significantly during the long-term follow-up of patients with spinal cord injury due to osteoporosis. This could be due to changes in hormonal and bone turnover markers.en_US
dc.identifier.doi10.1589/jpts.27.1429en_US
dc.identifier.endpage1433en_US
dc.identifier.issn0915-5287
dc.identifier.issn2187-5626
dc.identifier.issue5en_US
dc.identifier.pmid26157234en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage1429en_US
dc.identifier.urihttps://doi.org/10.1589/jpts.27.1429
dc.identifier.urihttps://hdl.handle.net/11454/42282
dc.identifier.volume27en_US
dc.identifier.wosWOS:000356074700034en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSoc Physical Therapy Scienceen_US
dc.relation.ispartofJournal of Physical Therapy Scienceen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBone lossen_US
dc.subjectSpinal cord injuryen_US
dc.subjectBone mineral densityen_US
dc.titleLongitudinal study of bone loss in chronic spinal cord injury patientsen_US
dc.typeArticleen_US

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