Serum soluble interleukin-2 receptors and tumor necrosis factor-? in hematological malignancies of childhood

Basit Öğe Kaydı
dc.contributor.authorÇETINGÜL N.
dc.contributor.authorYENER E.
dc.contributor.authorÖZTOP S.
dc.contributor.authorNIŞLI G.
dc.date.accessioned2019-10-27T00:33:45Z
dc.date.available2019-10-27T00:33:45Z
dc.date.issued1994
dc.departmentEge Üniversitesien_US
dc.description.abstractThe levels of soluble interleukin-2 receptors (sIL-2R) and tumor necrosis factor (TNF) were determined in the serum of 61 children with hematological malignancy, including 20 patients with leukemia and 16 with lymphoma in active state of malignancy, and 20 patients with leukemia and 5 with lymphoma in complete remission. In addition, serum samples from 15 healthy children were used as controls. It was found that the mean serum levels of sIL-2R and TNF were significantly increased in active malignancy (207.0±17.1 pmol/L for sIL-2R; 209.7±35.0 pg/mL for TNF) compared to the remission status and normal controls (P<0.001). No such difference was observed between leukemia and lymphoma groups. It was concluded that serum sIL-2R and TNF are of potential value in the diagnosis and follow up of patients with neoplastic diseases. 1994 Japan Pediatric Societyen_US
dc.identifier.doi10.1111/j.1442-200X.1994.tb03128.xen_US
dc.identifier.endpage52en_US
dc.identifier.issn1328-8067
dc.identifier.issue1en_US
dc.identifier.pmid8165908en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage49en_US
dc.identifier.urihttps://doi.org/10.1111/j.1442-200X.1994.tb03128.x
dc.identifier.urihttps://hdl.handle.net/11454/24123
dc.identifier.volume36en_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofPediatrics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectKey words malignancyen_US
dc.subjectsoluble interleukin-2 receptorsen_US
dc.subjecttumor necrosis factoren_US
dc.titleSerum soluble interleukin-2 receptors and tumor necrosis factor-? in hematological malignancies of childhooden_US
dc.typeArticleen_US

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