Effects of Preoperative Gabapentin on Postoperative Pain after Radical Retropubic Prostatectomy

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dc.contributor.authorDeniz, M. N.
dc.contributor.authorSertoz, N.
dc.contributor.authorErhan, E.
dc.contributor.authorUgur, G.
dc.date.accessioned2019-10-27T21:40:49Z
dc.date.available2019-10-27T21:40:49Z
dc.date.issued2012
dc.departmentEge Üniversitesien_US
dc.description.abstractOBJECTIVE: The impact of preoperative gabapentin on tramadol consumption using patient-controlled analgesia (PCA) and postoperative pain was assessed in patients undergoing radical retropubic prostatectomy (RRP). METHODS: In this prospective, randomized trial, 51 patients undergoing RRP were randomized into two groups: the gabapentin group received 900 mg gabapentin orally 2 h before surgery; the control group did not receive gabapentin. Postoperative analgesia was provided by tramadol PCA. Pain was assessed using a visual analogue scale for, 24 h, postoperatively. RESULTS: Mean cumulative tramadol consumption at 24 h was comparable in the two groups. Pain scores at 45 min, 60 min and 2 h postoperatively, and the number of patients who required rescue analgesia, were significantly lower in the gabapentin group than in the control group. Side-effects were similar in the two groups. CONCLUSIONS: Preoperative administration of 900 mg gabapentin did not decrease tramadol consumption, but was associated with lower pain scores in the early postoperative phase and a reduced need for rescue analgesia, compared with controls, in patients undergoing RRP.en_US
dc.identifier.doi10.1177/030006051204000635en_US
dc.identifier.endpage2369en_US
dc.identifier.issn0300-0605
dc.identifier.issn1473-2300
dc.identifier.issue6en_US
dc.identifier.pmid23321194en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage2362en_US
dc.identifier.urihttps://doi.org/10.1177/030006051204000635
dc.identifier.urihttps://hdl.handle.net/11454/46395
dc.identifier.volume40en_US
dc.identifier.wosWOS:000313538300035en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSage Publications Ltden_US
dc.relation.ispartofJournal of International Medical Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGABAPENTINen_US
dc.subjectPOSTOPERATIVE PAINen_US
dc.subjectRADICAL RETROPUBIC PROSTATECETOMYen_US
dc.subjectRESCUE ANALGESIAen_US
dc.subjectTRAMADOL CONSUMPTIONen_US
dc.titleEffects of Preoperative Gabapentin on Postoperative Pain after Radical Retropubic Prostatectomyen_US
dc.typeArticleen_US

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