Extrinsic factors influencing gut microbes, the immediate consequences and restoring eubiosis

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dc.contributor.authorBajinka, Ousman
dc.contributor.authorTan, Yurong
dc.contributor.authorAbdelhalim, Khalid A.
dc.contributor.authorOzdemir, Guven
dc.contributor.authorQiu, Xiangjie
dc.date.accessioned2020-12-01T11:58:53Z
dc.date.available2020-12-01T11:58:53Z
dc.date.issued2020
dc.departmentEge Üniversitesien_US
dc.description.abstractFrom the emerging studies, the more diverse the microbial population in the gut, the healthier the gut. Health benefits are associated with the functional characteristics of these diverse microbial genes. Extrinsic factors causing dysbiosis are extensively studied however, linking the varying degree of consequences to the respective factors and therapeutic possibilities are not explored at length. This review aims to examine from previous studies and put forward the types of dysbiosis, the immediate consequences and the scientific approaches to restore disrupted microbiota. Dietary supplements are found to be one of the factors contributing profoundly to the alteration of gut microbiota. While diet rich in fibre and fermented food established a diverse microbiome and produce vital metabolites, high fat, animal proteins and high caloric carbohydrate are as well relative to dysbiosis among infants, adult or diseases individuals. the intermittent fasting, feeding methods, the pH and water quality are among the factors associated with dysbiosis. Prebiotics and Probiotics maintain and restore gut homeostasis. Antibiotic-induced dysbiosis are relatively on the spectrum of activity, the pharmacokinetics properties, the dose taken during the treatment route of administration and the duration of drug therapy. the higher the altitude, the lesser the diversity. Extreme temperatures as well are related to reduced microbial activity and metabolism. Delivery through caserium-section deprived the newborn from restoring valuable vaginal bacterial species and the baby will instead assumed intestinal microbiota-like. While exercise and oxidative stress contribute even though moderately, fecal microbial transfer (FMT) also influence gut microbiota.en_US
dc.description.sponsorshipCentral South Universityen_US
dc.description.sponsorshipThe publication fee will be reimbursed by Central South Universityen_US
dc.identifier.doi10.1186/s13568-020-01066-8en_US
dc.identifier.issn2191-0855
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85088392793en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.urihttps://doi.org/10.1186/s13568-020-01066-8
dc.identifier.urihttps://hdl.handle.net/11454/62136
dc.identifier.volume10en_US
dc.identifier.wosWOS:000555866000001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofAmb Expressen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectGut microbiotaen_US
dc.subjectDysbiosisen_US
dc.subjectMediterranean dieten_US
dc.subjectInflammatory bowel diseasesen_US
dc.titleExtrinsic factors influencing gut microbes, the immediate consequences and restoring eubiosisen_US
dc.typeReview Articleen_US

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