Factors determining the response to treatment in patients with vestibular migraine

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dc.authorscopusid57214084021
dc.authorscopusid6603951334
dc.authorscopusid57201367527
dc.authorscopusid6506799839
dc.authorscopusid57318319200
dc.authorscopusid57201479700
dc.authorscopusid14036373700
dc.authorwosidÖzçelik, Pınar/AAE-6321-2021
dc.authorwosidErtaşoğlu Toydemir, Hülya/AHC-2763-2022
dc.contributor.authorAk, Aysin Kisabay
dc.contributor.authorCelebisoy, Nese
dc.contributor.authorOzdemir, Huseyin Nezih
dc.contributor.authorGokcay, Figen
dc.contributor.authorDurmaz, Gulsum Saruhan
dc.contributor.authorKarti, Dilek Top
dc.contributor.authorToydemir, Hulya Ertasoglu
dc.date.accessioned2023-01-12T19:59:07Z
dc.date.available2023-01-12T19:59:07Z
dc.date.issued2022
dc.departmentN/A/Departmenten_US
dc.description.abstractPurpose To find out clinical features associated with poor response to treatment in vestibular migraine (VM) Methods VM patients treated with drugs recommended in migraine prophylaxis were included in this multicenter study. Migraine features including type, age of onset of headache and vertigo attacks, attack frequency, intensity, associated symptoms, triggering factors, presence of interictal dizziness/imbalance, anxiety, depression, history of motion sickness, and family history of migraine were noted. Amitriptyline, flunarizine, propranolol, topiramate and venlafaxine were chosen depending on patients' individual requirements. Maximum dose of each drug was tried for 2 months to decide its efficacy. In the case of inefficacy, it was changed with another preventive drug of different class. If there was still no improvement, two drugs of different classes were combined. >= 50% reduction in attack frequency and severity in patients using one drug and a combination of two drugs was compared, with patients showing <50% reduction despite combination therapy, regarding their clinical features. Results The results of 430 VM patients, 65 men and 365 women with a mean age of 42.2 +/- 12.2 years (range: 17-74 years), were analyzed. Conclusion Cutaneous allodynia frequently associated with female sex, comorbid anxiety and depression and interictal dizziness/imbalance enhanced with comorbid anxiety were risk factors for reduced treatment response. Aural fullness might be the clue of impending concomitant Meniere's disease not responding to migraine preventives.en_US
dc.identifier.doi10.1080/01616412.2022.2056341
dc.identifier.endpage854en_US
dc.identifier.issn0161-6412
dc.identifier.issn1743-1328
dc.identifier.issue9en_US
dc.identifier.pmid35348034en_US
dc.identifier.scopus2-s2.0-85127951592en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage847en_US
dc.identifier.urihttps://doi.org/10.1080/01616412.2022.2056341
dc.identifier.urihttps://hdl.handle.net/11454/77100
dc.identifier.volume44en_US
dc.identifier.wosWOS:000774689800001en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTaylor & Francis Ltden_US
dc.relation.ispartofNeurological Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectVestibular migraineen_US
dc.subjecttreatmenten_US
dc.subjectallodyniaen_US
dc.subjectdizzinessen_US
dc.subjectimbalanceen_US
dc.subjectanxietyen_US
dc.subjectdepressionen_US
dc.subjectMenieres-Diseaseen_US
dc.subjectCutaneous Allodyniaen_US
dc.subjectSex-Differencesen_US
dc.subjectVertigoen_US
dc.subjectPainen_US
dc.subjectSymptomsen_US
dc.subjectHeadacheen_US
dc.subjectProphylaxisen_US
dc.subjectFeaturesen_US
dc.subjectAssociationen_US
dc.titleFactors determining the response to treatment in patients with vestibular migraineen_US
dc.typeArticleen_US

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