A neglected causative agent in diabetic foot infection: a retrospective evaluation of 13 patients with fungal etiology

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dc.contributor.authorOzturk, Anil Murat
dc.contributor.authorTasbakan, Meltem Isikgoz
dc.contributor.authorMetin, Dilek Yesim
dc.contributor.authorYener, Can
dc.contributor.authorUysal, Serhat
dc.contributor.authorYildirim Simsir, Ilgin
dc.contributor.authorErtam, Ilgen
dc.contributor.authorPullukcu, Husnu
dc.contributor.authorArda, Bilgin
dc.contributor.authorCetinkalp, Sevki
dc.date.accessioned2019-10-27T09:59:11Z
dc.date.available2019-10-27T09:59:11Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground/aim: Clinicians often neglect fungal infections and do not routinely investigate deep tissue from the wound for fungal culture and sensitivity due to insufficient information in the literature. In this study, we aimed to evaluate fungal etiology of invasive fungal diabetic foot which is rarely reported in the literature. Materials and methods: The patients who were unresponsive to antibiotic therapy and those with positive fungal in bone or deep tissue culture were enrolled in the study. Detailed hospital records were retrieved for demographics and clinical features. Results: A total of 13 patients who were diagnosed with invasive fungal diabetic foot (ten females, three males, mean age 59.8 +/- 9 years) were included. All of the patients had type-2 diabetes mellitus. Eleven (84.6%) patients had mixed infection. The most common cause of fungal infections of diabetic foot ulcers was the Candida species. Ten (76.9%) patients underwent amputation, two (15.4%) patients refused amputation, and one patient died before surgery. Conclusion: Invasive fungal infections may also be a causative pathogen in deep tissue infections. Therefore, fungal pathogens should be considered in patients unresponsive to long-term antibiotic therapy. Early detection of fungal infections in high-risk individuals is critical for the prevention of severe consequences such as foot amputation.en_US
dc.identifier.doi10.3906/sag-1809-74en_US
dc.identifier.endpage86en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.pmid30761877en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage81en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1809-74
dc.identifier.urihttps://hdl.handle.net/11454/29577
dc.identifier.volume49en_US
dc.identifier.wosWOS:000458367000012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technical Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectInvasive fungal infectionen_US
dc.subjectfoot infectionen_US
dc.subjectamputationen_US
dc.subjectdiabetic foot ulceren_US
dc.titleA neglected causative agent in diabetic foot infection: a retrospective evaluation of 13 patients with fungal etiologyen_US
dc.typeArticleen_US

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