Yazar "Zeybek U." seçeneğine göre listele

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    Comparison of the effects of Artemisia vulgaris and Artemisia absinthium growing in western Anatolia against trichinellosis (Trichinella spiralis) in rats
    (2008) Caner A.; Döşkaya M.; Degirmenci A.; Can H.; Baykan S.; Üner A.; Başdemir G.; Zeybek U.; Gürüz Y.
    Trichinellosis often causing diarrhea and more rarely fever, periorbital edema and myositis in human, is commonly treated with benzimidazole derivatives. The Artemisia genus has been found to be effective against a variety of parasites. In the present study, the efficacy against trichinellosis (Trichinella spiralis) of Artemisia vulgaris and Artemisia absinthium was examined for the first time in rats. The results of trichinoscopy and artificial digestion, during the enteral (adult) phase of the illness show that 300 mg/kg doses of methanol extracts of the aerial parts of A. vulgaris and A. absinthium reduced the larval rate by 75.6% and 63.5% in tongue, 53.4% and 37.7% in diaphragm, 67.8% and 46.2% in quadriceps, and 66.7% and 60.5% in biceps-triceps muscles of rats, respectively. Furthermore, during the parenteral (encapsulated larvae) phase, 600 mg/kg doses of A. vulgaris and A. absinthium extracts decreased the larval rate by 66.4% and 59.9% in tongue, 57.4% and 50.0% in diaphragm, 47.6% and 43.7% in quadriceps, 60.2% and 46.4% in biceps-triceps muscles of rats, respectively. Analysis of antibody also showed that A. vulgaris significantly reduced the antibody response (P < 0.05) during the enteral and parenteral phases. Thus, the results of the present study revealed that A. vulgaris could be an alternative drug against trichinellosis. © 2008 Elsevier Inc. All rights reserved.
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    Composition and antimicrobial activity of the essential oils of Achillea nobilis L. subsp. sipylea and subsp. neilreichii
    (2007) Karamenderes C.; Karabay Yavasoglu N.U.; Zeybek U.
    [No abstract available]
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    Composition and antimicrobial activity of the essential oils of Achillea Setacea waldst.&kit. collected from different localities of Turkey [Türki·ye'ni·n farkli lokali·teleri·nden toplanan Achillea Setacea waldst. & kit. uçucu yaginin bi·leşi·mi· ve anti·mi·krobi·yal akti·vi·tesi·]
    (2003) Karamenderes C.; Karabay N.U.; Zeybek U.
    Main components of the essential oils obtained by hydrodistillation from Achillea setacea collected from seven different localities of Turkey were determined by GC and GC/MS analyses and invitro antimicrobial activities of these essential oils were investigated in this study. Major component of A. setacea collected from Edirne, Tekirdag, Nigde, Kirşehir, Kirklareli and Burdur was determined as 1,8-cineole (35.4-48.5-34.3-36.7-38.2-42.3%, respectively). A.setacea collected from Sivas consists chamazulene and the major component was found to be camphor (30.2%). All of the essential oils were tested for in vitro antimicrobial activity for 3 gram-positive, 5 gram-negative bacteria and Candida albicans fungus with microdilution method. The essential oils showed antimicrobial activity against Proteus vulgaris, Salmonella thyphimurium and Candida albicans with concentration of 5%.
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    Composition and antimicrobial activity of the essential oils of some Achillea L. Species in Turkey
    (2002) Karamenderes C.; Karabay N.U.; Zeybek U.
    The composition and antimicrobial activity of essential oils obtained from Achillea millefolium L. subsp. pannonica (Scheele) Hayek, A millefolium L. subsp. millefolium, A. crithmifolia Waldst&Kitt. and A. kotschyi Boiss. subsp. kotschyi of Turkish flora were investigated. 1,8-cineole (43.3%) in A. millefolium L. subsp. pannonica, artemisia alcohol (37.2%) in A. millefolium subsp. millefolium, ascaridole (27.2%) in A. crithmifolia and 1,8-cineole (20.8%) in A. kotschyi essential oil were identified as major components by GC and GC/MS analysis. The essential oils showed antibacterial and antifungal effect even with low concentrations.
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    The importance of artemisia annua L. in The anticancer activity research [Antikanser aktivite araştirmalarinda artemisia annua L. bitkisinin önemi]
    (University of Ankara, 2017) Yalçinkaya E.; Özgüç S.; Aydinalp A.; Zeybek U.
    Objective: Cancer is known as one of the main cause of death worldwide. It is difficult to discover novel agents that selectively kill tumor cells or inhibit their proliferation without general toxicity. Searching for more active, more selective and less toxic compounds are the main targets of cancer researches. Artemisia annua L. has been used for a long time as a medicinal plant in Traditional Chinese Medicine (TCM). Artemisinin, which is one of the active compounds of this plant. It has antiviral, antiinflammatory, antiparasitic, antiallergic, antifibrotic, antiarrhythmic, immunmodulator, antitumorigenic, cytotoxic properties. The aim of this study is to review the A. annua compounds and search for their effects against various cancer cell lines. © 2018 University of Ankara. All rights reserved.
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    In vitro Investigation of the Pediculicidal Activities of the Volatile Oil Components of Some Medical Plants Raised in Turkey
    (2017) Limoncu M.E.; Balcıoğlu C.; Oyur T.; Zeybek G.; Zeybek U.
    OBJECTIVE: The human head louse Pediculus capitis has recently acquired resistance to commercially available insecticides, which has expanded the search concerning the pediculicidal activities of some herbal products. The present study aimed to assess the in vitro pediculicidal activities of volatile oils extracted from 10 medical plants raised in Turkey: Rosa damascena (red provins rose), Pelargonium graveolens (geranium), Lavandula angustifolia (lavender), Salvia triloba (salvia), Rosmarinus officinalis (rosemary; two different chemotypes), Citrus bergamia (citrus tree), Cymbopogon nardus (citronella), Citrus limonum (lemon), and Cymbopogon flexuosus (lemongrass).METHODS: Head lice obtained from school children in Manisa Province were initially grouped as adults and nymphs and were then kept under optimal conditions (temperature of 27°C and humidity of 50%). A pinch of hair and filter paper were placed in Petri dishes and seven adults and seven nymphs were separately put in Petri dishes. The extracts obtained from each volatile oil were dropped on the lice specimens.RESULTS: The active movement of the external (antenna and legs) and internal (midgut and intestine) organs of the lice was monitored and recorded starting from 5th min for 24 hours by 10 to 30 minutes intervals. The time of death was defined as the loss of active movement and cessation of intestinal activities of lice. The results were analyzed using Statistical Packages for the Social Sciences (SPSS) version 15.CONCLUSION: The results showed that the volatile oil of Rosmarinus officinalis (two different chemotypes) was more effective than the other oils.
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    The influence of chernobyl on the radiocesium contamination in lichens in Turkey
    (1992) Topcuog˜lu S.; Küçükcezzar R.; Güngör N.; Bayülgen N.; Zeybek U.; Cevher E.; Güvener B.; John V.; Güven K.C.
    Lichen samples collected before and after the Chernobyl accident were analysed for radiocesium activity. 137Cs activity was detected in some samples collected before Chernobyl. 134Cs and 137Cs were detected in all the samples after the accident. The levels of the total cesium activity counted in the samples proved that the eastern region of the Black Sea was affected by Chernobyl at a very high degree compared with other parts of Turkey. © 1992, Taylor & Francis Group, LLC. All rights reserved.
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    Medicinal plants and their secondary metabolites effective against breast cancer [Meme kanserinde etkili tibbi bitkiler ve sekonder metabolitleri]
    (University of Ankara, 2018) Özgüç S.; Kayalar H.; Zeybek U.
    Objective: This study aims at reviewing an evidence-based approach to medicinal plants for the supportive treatment of breast cancer. Material and Method: The subject databases for health sciences are considered for comprehensive search of the literature in terms of medicinal plants for the treatment of breast cancer. An electronic search for previously published articles was conducted in Medline citations and key citation indexes such as Scopus and Web of Science. Result and Discussion: A certain part of the medicines used in breast cancer are derived from plants. Some plants can protect the body from malignancy with their detoxification mechanism. Some medicinal plants that modify the biological response can prevent cancer development by modifying activities of hormones and enzymes. Some plants can support the treatment by reducing the side effects of chemotherapy and radiotherapy. In this review, in addition to 14 medicinal plants some sources consumed as fruits and vegetables. that may have potential effects on breast cancer are discussed. Although Turkey is one of the richest countries in terms of large flora and endemic medicinal plants, sufficient number of cancer research and clinical trials on breast cancer are not considered enough. © 2018 Tasar?m / Design Kayhan Bolelli.
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    Studies on the northeast Anatolian lichens Lobaria scrobiculata and L. pulmonaria [Untersuchungen uber die nordost - Anatolischen flechten lobaria scrobiculata und L. pulmonaria]
    (Osterreichische Apotheker-Verlagsgesellschaft m.b.H., 2000) Zeybek U.; Yildiz A.
    The secondary metabolites in Lobaria pulmonaria and L. scrobiculata collected in northeast Anatolia are studied using HPLC. Constictic, nortictic and stictic acids are the major components in L. pulmonaria; in addition connorstictic, cryptostictic, and menegazziaic acids are present as minor constituents. In L. scrobiculata constictic, stictic, and usnic acids and m- scrobiculin are the major compounds; while cryptostictic and norstictic acids, and p- scrobiculin are present as minors.
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    A taxonomical investigation into Turkey lichen genus Hypogymnia (Nyl.) Nyl. [Turkiye Likenlerinden Hypogymnia (Nyl.) Nyl. cinsi uzerinde taksonomik arastirma]
    (1993) Zeybek U.; John V.; Lumbsch H.T.
    Six species are recorded: Hypogymnia bitteri, H. farinacea, H. laminisorediata, H. physodes, H. tubulosa and H. vitta. Distribution maps of these species are given. A key to the Turkish species is presented, as well as a morphological description of the species and their chemistry. -from English summary