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Öğe The "extreme" errors in inhaler device use: data from the INTEDA-1 study(Wiley-Blackwell, 2011) Caliskaner, Z.; Ozturk, C.; Pekcan, S.; Yilmaz, O.; Ozturk, S.; Ceylan, E.; Can, C.; Sener, O.; Turay, U.; Ersoy, R.Öğe Food Allergy due to Olive(Esmon Publicidad S A, 2009) Unsel, M.; Ardeniz, Oe; Mete, N.; Ersoy, R.; Sin, A. Z.; Gulbahar, O.; Kokuludag, A.We report the case of a 28-year-old man who presented palatal itching and genaralized urticaria following ingestion of olive 3 years after being diagnosed with olive pollinosis. The patient did not have a history of food allergy or urticaria. The results of skin prick tests with aeroallergens including latex were positive for house dust mite and olive pollen. The results of prick tests and prick-to-prick tests for olive fruit were positive, as were those of specific immunoglobulin E tests to olive pollen and fruit. The results of prick tests to peach, pear, kiwi, melon, and nut were negative. Nasal provocation with olive pollen gave positive results. An open oral provocation test with olive oil did not cause symptoms. This case is unique in that the patient developed olive fruit allergy in the presence of olive pollinosis, and he did not experience allergic symptoms to fruits other than olive, thus enabling us to define a new pollen-food (olive-olive) syndrome.Öğe The importance of nasal provocation test in the diagnosis of natural rubber latex allergy(Wiley-Blackwell Publishing, Inc, 2009) Uensel, M.; Mete, N.; Ardeniz, Oe; Goeksel, S.; Ersoy, R.; Sin, A.; Gulbahar, O.; Kokuludag, A.Most studies regarding natural rubber latex (NRL) allergy have concentrated on the prevalance using skin prick test (SPT) and specific IgE assay. The objective of this study is to examine the target organ (skin, nasal mucosa) responses in patients with positive SPT to NRL using the nasal provacation test (NPT) and glove use test (GUT). Four thousand four hundred and twenty patients presented to our polyclinic between July 2003 and January 2007 were evaluated. One thousand six hundred and ninety-nine patients had positive SPT to one or more allergens (NRL and other inhaler allergens). Twenty-nine patients with positive SPT to NRL comprised the NRL sensitive group (group 1). Thirty-five randomized patients with positive SPT to an inhaler allergen other than NRL and negative NRL-specific IgE comprised atopic control group (group 2). Thirty healthy individuals who had no allergic diseases and had negative SPT and NRL-specific IgE comprised the healthy control group (group 3). The lowest NRL allergen concentration leading to NPT positiveness was 0.05 mu g/mL. NPT was negative in groups 2 and 3. NPT was found to have a sensitivity of 96%, specificity of 100%, negative predictive value of 98% and positive predictive value of 100%. GUT was found to have a sensitivity of 81%, specificity of 90%, negative predictive value of 75% and positive predictive value of 93%. Nasal provocation test was successfully used for the first time in the diagnosis of NRL allergy. NPT is a more sensitive method as compared to GUT.Öğe New onset egg allergy in an adult(Esmon Publicidad S A, Dept Allergy & Clin Immunol, Clin Univ Navarra, 2007) Uensel, M.; Sin, A. Z.; Ardeniz, Oe; Erdem, N.; Ersoy, R.; Gulbahar, O.; Mete, N.; Kokuludag, A.We report newly presenting systemic and local allergic reactions to egg in a 55-year-old woman. The patient did not have a history of egg allergy in childhood or occupational exposure to egg proteins; nor did she report any disease that is known to be related to food allergy. A skin prick test with commercial extracts, prick-to-prick test, CAP radioallergosorbent assay, and a double-blind, placebo-controlled food challenge test were used to prove egg allergy. Because egg allergy mainly affects children and symptoms frequently disappear with age, the late onset in this patient is rare.Öğe Physicians' knowledge of and opinions about inhaler treatments in asthma and COPD: the INTEDA-1 study(Wiley-Blackwell, 2011) Caliskaner, Z.; Ozturk, C.; Pekcan, S.; Yilmaz, O.; Ozturk, S.; Ceylan, E.; Can, C.; Sener, O.; Turay, U.; Ersoy, R.Öğe Prevalence of cypress pollen sensitization and its clinical importance in Izmir, Turkey, with cypress allergy assessed by nasal provocation(Esmon Publicidad S A, 2008) Sin, A. Z.; Ersoy, R.; Gulbahar, O.; Ardeniz, O.; Gokmen, N. M.; Kokuludag, A.Background and objective: Pollens from the Cupressaceae family are considered important allergens in the Mediterranean area, though reports of the prevalence of allergic symptoms have ranged from 1.04% to 35.4%. Our aim was to detect the prevalence of cypress pollen sensitization and determine its clinical importance in patients with seasonal respiratory allergy. Methods: We used skin prick tests (SPT) and serum specific IgE assays to reveal sensitization to cypress pollen. In patients who showed positive results to cypress pollen, a nasal provocation test (NPT) with pollen extract was used to assess the target organ response. Results: Sixty-five (14.3%) of 455 patients showed positive SPT responses to Cupressus sempervirens extract. Only I patient was monosensitized while 64 patients were polysensitized. Among those, 2 pollen cosensitizations were found to be significant (86% were cosensitized to grasses and 72% were cosensitized to olive (P <.001). Serum specific IgE to cypress pollen was measured in 50 of the 65 patients; findings were positive for 37. When these 37 patients underwent NPT with C sempervirens allergen extract, only the single monosensitized patient had a positive NPT. Conclusion: A positive SPT to cypress pollen may not reflect the true prevalence of sensitization. We assume that in the absence of a positive NPT, positive SPT results might be related to the presence of cross-reactivity between pollen species.Öğe What do we know about systemic hymenoptera allergy in Turkey? What happens before the patients reach an allergy clinic?(Wiley-Blackwell, 2011) Gulbahar, O.; Ural, C.; Ersoy, R.; Gurlek, F.; Koc, Z.; Ardeniz, O.; Gokmen, N.; Sin, A.; Kokuludag, A.
