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Öğe Characteristics of optic neuropathy in Behçet disease(Lippincott Williams and Wilkins, 2018) Akdal G.; Toydemir H.E.; Saatci A.O.; Uygunoglu U.; Altunrende B.; Saip S.; Yaman A.; Keskino P.; Yılmaz S.G.; Çelebisoy N.; Bajin M.S.; Siva A.; Akman-Demir G.Objective: We present the clinical profile, features, and neuroimaging findings of 25 patients with Behçet disease (BD), and optic neuropathy (ON), which has been rarely reported in BD. Methods: Data from 5 university hospitals were retrospectively reviewed, and patients with BD and ON were evaluated. There were 2 groups: (1) those already diagnosed with BD when ON developed (BD›ON group) and (2) those diagnosed with BD during the evaluation of ON (ON›BD group). Results: There were 25 BD patients with ON (13 males). Among these, 13 had ON›BD, and 12 had BD›ON. Seventeen patients had unilateral ON, and 7 patients had recurrent ON. BD›ON patients were older. Disc edema was seen more in ON›BD than in BD›ON patients (10 vs 3). Fourteen patients also had uveitis, 7 with BD›ON and 7 with ON›BD. There was other neurologic involvement in 8 patients; in the BD›ON group, 4/4 had MS-like disease, in the ON›BD group, 3 had typical parenchymal BD, and 1 had MS-like disease. Twenty of 21 patients received immunosuppressive medications, corticosteroids, or both. Prognosis was favorable in most: vision improved in 20 patients, more often in those receiving combined therapies. Conclusion: BD may be diagnosed earlier if it is considered and investigated during the assessment of ON, particularly in high-risk regions. Prognosis of ON related to BD seems to be favorable. Immunosuppressants should be given along with corticosteroids. MS-like presentations should also be kept in mind in patients with BD and ON. Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.Öğe Pseudotumor cerebri syndrome without cerebral venous sinus thrombosis in Behçet's disease(Elsevier B.V., 2017) Akdal G.; Yaman A.; Men S.; Çelebisoy N.; Toydemir H.E.; Bajin M.S.; Akman-Demir G.[No abstract available]
