Characteristics of optic neuropathy in Behçet disease
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Lippincott Williams and Wilkins
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: We present the clinical profile, features, and neuroimaging findings of 25 patients with Behçet disease (BD), and optic neuropathy (ON), which has been rarely reported in BD. Methods: Data from 5 university hospitals were retrospectively reviewed, and patients with BD and ON were evaluated. There were 2 groups: (1) those already diagnosed with BD when ON developed (BD›ON group) and (2) those diagnosed with BD during the evaluation of ON (ON›BD group). Results: There were 25 BD patients with ON (13 males). Among these, 13 had ON›BD, and 12 had BD›ON. Seventeen patients had unilateral ON, and 7 patients had recurrent ON. BD›ON patients were older. Disc edema was seen more in ON›BD than in BD›ON patients (10 vs 3). Fourteen patients also had uveitis, 7 with BD›ON and 7 with ON›BD. There was other neurologic involvement in 8 patients; in the BD›ON group, 4/4 had MS-like disease, in the ON›BD group, 3 had typical parenchymal BD, and 1 had MS-like disease. Twenty of 21 patients received immunosuppressive medications, corticosteroids, or both. Prognosis was favorable in most: vision improved in 20 patients, more often in those receiving combined therapies. Conclusion: BD may be diagnosed earlier if it is considered and investigated during the assessment of ON, particularly in high-risk regions. Prognosis of ON related to BD seems to be favorable. Immunosuppressants should be given along with corticosteroids. MS-like presentations should also be kept in mind in patients with BD and ON. Copyright © 2018 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology.
Açıklama
Anahtar Kelimeler
Kaynak
Neurology: Neuroimmunology and NeuroInflammation
WoS Q Değeri
Scopus Q Değeri
Q1
Cilt
5
Sayı
5
