Yazar "Askar N." seçeneğine göre listele
Listeleniyor 1 - 6 / 6
Sayfa Başına Sonuç
Sıralama seçenekleri
Öğe Effect of gestational diabetes and smoking on the elemental status of the maternal fetal placental unit(1996) Coker C.; Aydin H.; Askar N.; Ersoz B.; Akercan F.Objective: This study is undertaken to investigate the effects of gestational diabetes and smoking on the elemental status of the maternal-fetal-placental unit. Methods: Concentrations of Cu, Zn, Fe, Mg and Ca are determined in placental tissue, maternal and fetal plasma and fetal red blood cell samples obtained during delivery (group 1 gestational diabetes, n = 8; group 2 smoking, n = 8; group 3 healthy controls, n = 9). The elemental analysis is performed by inductively coupled atomic emission spectrophotometry. Results: The diabetes group shows no significant differences with respect to the elemental status of maternal and fetal plasma and fetal red blood cells. The only significant variation is observed in placental Fe (p < 0.05). In the smoking group, significant decreases are determined in placental Ca (p < 0.05), maternal plasma Zn, Mg and Ca (p < 0.05), along with fetal plasma Mg (p < 0.01) and Ca (p < 0.05) levels. Conclusion: The results are indicative of variations in perinatal elemental metabolism in abnormal states of pregnancy, especially smoking, however the mechanisms underlying these alterations are yet to be elucidated.Öğe Effect of placenta previa on fetal growth restriction and stillbirth(2012) Yeniel A.O.; Ergenoglu A.M.; Itil I.M.; Askar N.; Meseri R.Aim: To examine the association between placenta previa and adverse perinatal outcomes such as low birth weight, preterm delivery, stillbirth and fetal growth restriction (FGR). Methods: This retrospective cohort study includes 12,034 delivered pregnant women who were recruited for the study between 2004 and 2010 in Ege University Hospital. Data were collected by browsing the clinic's archives. The association between placenta previa and adverse perinatal outcomes was determined via Chi-square tests and Student's t test. Logistic regression analysis was used to adjust for confounding factors in evaluating the association between placenta previa and the adverse perinatal outcomes. Results: There was no significant relationship between placenta previa and FGR or stillbirth. Low birth weight and preterm delivery were significantly higher in the placenta previa group. According to logistic regression analysis, low birth weight was associated with an OR of 3.01 (95 % CI 2.05-4.52) and preterm delivery was associated with an OR of 8.14 (95 % CI 5.60-11.83); while, placenta previa did not affect FGR and stillbirth significantly. Conclusion: Although there is no consensus on the association between placenta previa and FGR in previous studies, we suggest that placenta previa is not a reason for placental insufficiency. Management of placenta previa especially depends on maternal hemodynamic parameters such as heavy hemorrhage and hypotensive shock rather than fetal well-being protocols based on serial growth ultrasound and fetal Doppler investigation. © Springer-Verlag 2012.Öğe Elemental variations in preeclampsia(1996) Askar N.; Coker C.; Aydin H.H.; Ersox B.; Ates T.Objective: There are alterations in elemental metabolism due to physiological and pathological processes in pregnancy. In this study, the physiological distribution of elements between the mother and the fetus is investigated along with the variations in the elemental status of the maternal-fetal-placental unit in pregnancies complicated with preeclamptic toxemia. Methods: Cu, Zn, Fe, Mg and Ca levels in placental tissue, maternal and fetal plasma and fetal red blood cells in the healthy individuals (n = 9) and preeclamptics (n=10) are determined by inductively coupled plasma atomic emission spectrometry. Results: Within the control group, significant differences between maternal and fetal plasma have been detected with respect to Cu (p < 0.001) and Fe(p < 0.05) levels. Comparing the preeclamptics with the controls, the most marked variation is observed in Zn status with significantly decreased concentrations in maternal and fetal plasma (p < 0.05) and fetal red blood cells (p < 0.01). Significant variations are also determined for Cu in fetal red blood cells (p < 0.05), Ca in placental tissue (p < 0.01) and fetal plasma (p < 0.05). Conclusion: This study points out the disturbances in the elemental status of the maternal-fetal-placental unit in preeclampsia.Öğe Huge endometriosis presenting like an ovarian tumor: CT appearance(2010) Yerli H.; Askar N.; Zekioglu O.; Baglan Z.; Elmas N.A 32-year-old female with a clinical history of abdominal swelling underwent CT of the abdomen. A huge biloculated cystic mass with a mural nodule in the abdominal and pelvic region was seen. The lesion showed slightly homogeneous enhancement. The imaging findings suggested an ovarian tumor. Histopathological evaluation after surgical resection revealed that the lesion was a bilateral ovarian endometriosis.Öğe The prevalence of probable overactive bladder, associated risk factors and its effect on quality of life among Turkish midwifery students(Elsevier Ireland Ltd, 2012) Özgür Yeniel A.; Mete Ergenoglu A.; Meseri R.; Hadimli A.; Askar N.; Mete Itil I.Objectives: To evaluate the associated risk factors of probable overactive bladder (OAB) and to determine the effect of OAB on quality of life through validated questionnaires in Turkish midwifery students. Study design: 279 midwifery students were invited to participate, and 265 (95.0%) were included in the study, which was approved by the local ethics committees. The relationship between quality of life and probable OAB was evaluated using Turkish language-validated questionnaires (OABq SF, NQOL). Chi-square test, t-test and logistic regression were used for the statistical analysis, and p < 0.05 was considered significant. Results: The participants' mean age was 21.74 ± 2.15 years. The prevalence of OAB was 35.4%. There was a significant relationship between the presence of probable OAB and familial urinary incontinence history and childhood nocturnal enuresis. In the logistic regression analysis, family history was associated with an OR of 2.11 (95% CI: 1.08-4.10) for OAB, and nocturia with an OR of 2.69 (95% CI: 1.16-6.21) for OAB. Drinking moderate amounts of tea and carbonated drinks daily did not affect OAB, but extreme consumption of these beverages was associated with an OR of 2.98 (95% CI: 1.26-7.03) for OAB. OAB significantly worsens quality of life according to all the quality of life indices. Conclusion: OAB is not a rare condition among young people. It appears that the quality of life was adversely influenced by OAB among both younger and older people. Familial urinary incontinence and childhood nocturnal enuresis were found to be risk factors for OAB. There is insufficient evidence to restrict tea or carbonated drinks consumption in young people with OAB unless their consumption is extreme. © 2012 Elsevier Ireland Ltd. All rights reserved.Öğe Quality of life scores improve in women undergoing colpocleisis: A pilot study(Elsevier Ireland Ltd, 2012) Yeniel A.Ö.; Ergenoglu A.M.; Askar N.; Itil I.M.; Meseri R.Objective: To evaluate the quality of life and surgical outcomes in women who had undergone colpocleisis. Study design: This was a prospective small cohort study conducted between August 2010 and September 2011. Twelve women with pelvic organ prolapse were offered obliterative vaginal surgery and were informed about the surgical procedure. Ten women accepted this operation and were included in the study. Before and after colpocleisis, cases were evaluated by urogynecological examination, and quality of life was assessed by the Turkish language validated prolapse quality of life questionnaire (P-QOL), in which a low total score indicates a good quality of life. Results: The mean age was 74.9 ± 4.5 (range 68-85). The general score of the P-QOL was reduced during the follow-up period, reflecting a significant effect on quality of life and clinical improvement in women with the colpocleisis operation. There was no morbidity due to colpocleisis or recurrent pelvic organ prolapse in follow-up period. Conclusion: In our small cohort including elderly women, colpocleisis provided high levels of surgical outcomes as well as a significant improvement in quality of life without significant morbidity. © 2012 Elsevier Ireland Ltd.
