Effect of gestational diabetes and smoking on the elemental status of the maternal fetal placental unit
Küçük Resim Yok
Tarih
1996
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: This study is undertaken to investigate the effects of gestational diabetes and smoking on the elemental status of the maternal-fetal-placental unit. Methods: Concentrations of Cu, Zn, Fe, Mg and Ca are determined in placental tissue, maternal and fetal plasma and fetal red blood cell samples obtained during delivery (group 1 gestational diabetes, n = 8; group 2 smoking, n = 8; group 3 healthy controls, n = 9). The elemental analysis is performed by inductively coupled atomic emission spectrophotometry. Results: The diabetes group shows no significant differences with respect to the elemental status of maternal and fetal plasma and fetal red blood cells. The only significant variation is observed in placental Fe (p < 0.05). In the smoking group, significant decreases are determined in placental Ca (p < 0.05), maternal plasma Zn, Mg and Ca (p < 0.05), along with fetal plasma Mg (p < 0.01) and Ca (p < 0.05) levels. Conclusion: The results are indicative of variations in perinatal elemental metabolism in abnormal states of pregnancy, especially smoking, however the mechanisms underlying these alterations are yet to be elucidated.
Açıklama
Anahtar Kelimeler
Electrolytes, Gestational diabetes, Pregnancy, Smoking, Trace elements
Kaynak
Marmara Medical Journal
WoS Q Değeri
Scopus Q Değeri
Q4
Cilt
9
Sayı
3
