Evaluation of Ocular Surface and Meibomian Glands Alterations with Meibography in Patients with Inactive Behçet’s Uveitis

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dc.contributor.authorKaraca I.
dc.contributor.authorPalamar M.
dc.contributor.authorGuven Yilmaz S.
dc.contributor.authorAtes H.
dc.date.accessioned2019-10-27T08:00:59Z
dc.date.available2019-10-27T08:00:59Z
dc.date.issued2019
dc.departmentEge Üniversitesien_US
dc.description.abstractPurpose: To evaluate the ocular surface and meibography of patients with inactive Behçet’s uveitis. Methods: Twenty-five right eyes of 25 patients with inactive Behçet’s uveitis (Group 1) and 25 right eyes of 25 healthy individuals (Group 2) were enrolled. Detailed eye examination along with Schirmer 1 test, tear film break-up time (t-BUT), ocular surface staining with fluorescein and Oxford scoring, and ocular surface disease index (OSDI) score assessment were performed. Lower and upper eyelid Meibomian glands were examined with infrared filter of slit-lamp biomicroscope (SL-D701 with DC-4 digital camera and BG-5 background illuminator, TOPCON, Tokyo, Japan (from grade 0 (no dropout of Meibomian glands) to grade 3 (gland dropout >2/3 of the total Meibomian glands)). Results: The mean ages were 36.84 ± 7.39 (range, 23–59) and 33.88 ± 8.25 (range, 18–55) in Group 1 and Group 2, respectively (p = 0.547). When compared with Group 2, in Group 1, best-corrected visual acuity (0.28 vs. 0.00 logMAR, p < 0.001), Schirmer 1 test (18.68 vs. 23.69, p = 0.017) and mean tear film break-up time (10.76 vs. 13.36, p = 0.026) were significantly lower; Oxford scale and OSDI scores were higher (p = 0.039 and p < 0.001, respectively). No significant difference in lower, upper and total (upper + lower) meiboscores were detected in between groups (p = 0.062, p = 0.228 and p = 0.152, respectively). Conclusion: Despite the tendency toward dry eye syndrome, Behçet’s uveitis does not seem to be associated with quantitative Meibomian gland changes, which is demonstrated by gland drop-out with meibography. © 2018, © 2018 Taylor & Francis Group, LLC.en_US
dc.identifier.doi10.1080/02713683.2018.1555261
dc.identifier.endpage359en_US
dc.identifier.issn0271-3683
dc.identifier.issn0271-3683en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage356en_US
dc.identifier.urihttps://doi.org/10.1080/02713683.2018.1555261
dc.identifier.urihttps://hdl.handle.net/11454/24888
dc.identifier.volume44en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherTaylor and Francis Ltden_US
dc.relation.ispartofCurrent Eye Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBehçet’s uveitisen_US
dc.subjectdry eyeen_US
dc.subjectmeibographyen_US
dc.subjectMeibomian gland dysfunctionen_US
dc.subjectOcular surfaceen_US
dc.titleEvaluation of Ocular Surface and Meibomian Glands Alterations with Meibography in Patients with Inactive Behçet’s Uveitisen_US
dc.typeArticleen_US

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