Investigation of cell growth on ion beam patterns on GPC surface

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dc.contributor.authorZimmerman, R.
dc.contributor.authorMuntele, C.
dc.contributor.authorGurhan, I.
dc.contributor.authorOzdal-Kurt, F.
dc.contributor.authorSen, B. H.
dc.contributor.authorRodrigues, M.
dc.contributor.authorIla, D.
dc.date.accessioned2019-10-27T20:51:15Z
dc.date.available2019-10-27T20:51:15Z
dc.date.issued2009
dc.departmentEge Üniversitesien_US
dc.description15th International Conference on Surface Modification of Materials by Ion Beams -- SEP 30-OCT 05, 2007 -- Univ Mumbai, Mumbai, INDIAen_US
dc.description.abstractWe have used implanted silver ions near the surface of Glassy Polymeric Carbon (GPC) to completely inhibit cell attachment and adhesion to GPC. The effect improves the safety and function of the GPC heart valve exposed to the blood stream. The strength, durability and low density make GPC a favored material for in vivo medical applications, including transcutaneous electrodes and replacement heart valves. However, the possible release of endothelial tissue that forms on the smooth surfaces of the GPC heart valve has the potential of creating an embolism. We have shown that L929 endothelial cells avoid silver implanted areas of GPC but attach and strongly adhere to areas close to silver implanted surfaces. Patterned ion implantation permits precise control of tissue growth on GPC and other biocompatible substrates. Cell growth inhibited by silver ion implanted patterns on an otherwise biocompatible substrate may be useful for in vitro studies of the way that cells sense and move away from inhospitable environments. (C) 2009 Published by Elsevier B.V.en_US
dc.description.sponsorshipMat Res Soc India, Bhabha Atom Res Ctr, Tata Inst Fundamental Resen_US
dc.identifier.doi10.1016/j.surfcoat.2009.02.075
dc.identifier.endpage2561en_US
dc.identifier.issn0257-8972
dc.identifier.issn0257-8972en_US
dc.identifier.issue17-18en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage2558en_US
dc.identifier.urihttps://doi.org/10.1016/j.surfcoat.2009.02.075
dc.identifier.urihttps://hdl.handle.net/11454/43092
dc.identifier.volume203en_US
dc.identifier.wosWOS:000266682000049en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Saen_US
dc.relation.ispartofSurface & Coatings Technologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPatterned cell growthen_US
dc.subjectGlassy polymeric carbonen_US
dc.subjectIon implantationen_US
dc.titleInvestigation of cell growth on ion beam patterns on GPC surfaceen_US
dc.typeArticleen_US

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