Combined central and peripheral nervous system demyelination: A case report [Kombine santral ve periferik sinir sistemi demiyelinizasyonu: Bir olgu bidirimi]

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dc.contributor.authorKiliç İ.H.
dc.contributor.authorErdoğan C.E.
dc.contributor.authorAydin İ.
dc.contributor.authorGökçay F.
dc.contributor.authorYüceyar A.N.
dc.date.accessioned2019-10-27T08:04:25Z
dc.date.available2019-10-27T08:04:25Z
dc.date.issued2017
dc.departmentEge Üniversitesien_US
dc.description.abstractCombined central and peripheral nervous system demyelination (CCPD) is a fairly new concept and our knowledge is restricted to several case series and case reports. We aimed to contribute to the literature with our experiences in the management of a patient representing both chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) and multiple sclerosis (MS) features. A 32-year-male patient presented with neuropathic compaints for one year and recent onset of optic neuritis with central demyelinating lesions. Clinical, electrophysiological and radiological response was achieved with corticosteroid treatment and relapsed after cessation. His second simultaneous CCPD exacerbation did not respond on intravenous immunoglobulins (IVIG) but responded well on intravenous high dose corticosteroid. Previous studies reported inadequate responses to high-dose corticosteroids and IVIG in the majority of patients with CCPD. It's estimated to be a unique disease beyond MS and CIDP with heterogenous features. We suggest that awareness of this steroid-dependent condition may improve our knowledge in the pathophysiology and management strategies. © 2018, Ege University Press. All rights reserved.en_US
dc.identifier.doi10.24165/jns.10192.17
dc.identifier.endpage348en_US
dc.identifier.issn1300-1817
dc.identifier.issn1300-1817en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage343en_US
dc.identifier.urihttps://doi.org/10.24165/jns.10192.17
dc.identifier.urihttps://hdl.handle.net/11454/25513
dc.identifier.volume34en_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherEge University Pressen_US
dc.relation.ispartofJournal of Neurological Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectChronic inflammatory demyelinating polyneuropathyen_US
dc.subjectCombined central and peripheral demyelinationen_US
dc.subjectMultiple sclerosisen_US
dc.subjectOptic Neuritisen_US
dc.titleCombined central and peripheral nervous system demyelination: A case report [Kombine santral ve periferik sinir sistemi demiyelinizasyonu: Bir olgu bidirimi]en_US
dc.typeArticleen_US

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