Evaluation of Saccadic and Smooth Pursuit Eye Movements at an Early Stage of Essential Tremor

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dc.contributor.authorCelebisoy, Mehmet
dc.contributor.authorCelebisoy, Nese
dc.contributor.authorEkinci, Aysen Suzen
dc.contributor.authorAkyuz, Esra
dc.contributor.authorAcarer, Ahmet
dc.date.accessioned2019-10-27T23:12:18Z
dc.date.available2019-10-27T23:12:18Z
dc.date.issued2016
dc.departmentEge Üniversitesien_US
dc.description.abstractObjectives: Though still unclear cerebellar involvement is accepted as the underlying pathophysiological mechanism of at least advanced stages of essential tremor ( ET). Eye movement abnormalities supporting this hypothesis have been reported. We tried to investigate saccadic and pursuit eye movements in ET patients at an early stage of the disease (mean disease duration 20.35 +/- 10.51 months). Materials and Methods: Binocular horizontal saccadic and pursuit eye movements were recorded by using a video-based eye tracker in 25 patients with ET and 16 age matched controls. For the saccades peak saccadic velocity, latency and accuracy and for pursuit eye movements gain at three different target velocities (0.1, 0.2 and 0.4 Hz) was taken into consideration. Results: Peak saccadic latency, velocity and accuracy values recorded from the patients during saccadic eye movements were compared with the values gathered from the healthy controls revealing no significant difference (p>0.05). The same was true for pursuit eye movements. Pursuit gain at three different target velocities recorded from ET patients were not statistically different from the healthy controls (p>0.05). Conclusion: Normal eye movements at the early stage of the disease may indicate cerebellar dysfunction to be a late feature of ET. The other explanation can be the heterogeneous nature of the disease, those with abnormal eye findings representing a specific pathological subset.en_US
dc.identifier.endpage558en_US
dc.identifier.issn1302-1664
dc.identifier.issn1302-1664en_US
dc.identifier.issue4en_US
dc.identifier.startpage552en_US
dc.identifier.urihttps://hdl.handle.net/11454/53200
dc.identifier.volume33en_US
dc.identifier.wosWOS:000393047300004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherJournal Neurological Sciencesen_US
dc.relation.ispartofJournal of Neurological Sciences-Turkishen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEssential tremoren_US
dc.subjecteye movementsen_US
dc.subjectcerebellumen_US
dc.titleEvaluation of Saccadic and Smooth Pursuit Eye Movements at an Early Stage of Essential Tremoren_US
dc.typeArticleen_US

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