Antiprotozoal alkaloids from Galanthus trojanus

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dc.contributor.authorKaya, Gulen Irem
dc.contributor.authorSarikaya, Buket
dc.contributor.authorOnur, Mustafa Ali
dc.contributor.authorSomer, Nehir Unver
dc.contributor.authorViladomat, Francesc
dc.contributor.authorCodina, Carles
dc.contributor.authorBastida, Jaume
dc.contributor.authorLauinger, Ina L.
dc.contributor.authorKaiser, Marcel
dc.contributor.authorTasdemir, Deniz
dc.date.accessioned2019-10-27T21:36:22Z
dc.date.available2019-10-27T21:36:22Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractTwo new alkaloid N-oxides, 1-O-acetyldihydromethylpseudolycorine N-oxide, and 11-hydroxyvittatine N-oxide, ten known alkaloids; arolycoricidine, haemanthamine, O-methylnorbelladine, narcidine, dihydrolycorine, 8-O-demethylmaritidine, stylopine and protopine, nicotinic acid and tyramine were isolated from Galanthus trojanus A. P. Davis & N. Ozhatay (Amaryllidaceae). The chemical structures of the isolates were elucidated by UV, IR, MS, CD, 1D and 2D NMR experiments. The in vitro antiprotozoal and cytotoxic potentials of the compounds were also evaluated. (C) 2011 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkey (TUBITAK)Turkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK); Ege Science and Technology Center (EBILTEM)Ege Universityen_US
dc.description.sponsorshipThis study was financially supported by the Scientific and Technological Research Council of Turkey (TUBITAK) and by the Ege Science and Technology Center (EBILTEM). B. S. was a recipient of TUBITAK research fellowship. We thank Dr Remo Perozzo for his initial help in enzyme assays. I. L. L. thanks the London School of Pharmacy for PhD scholarship.en_US
dc.identifier.doi10.1016/j.phytol.2011.05.008
dc.identifier.endpage305en_US
dc.identifier.issn1874-3900
dc.identifier.issn1874-3900en_US
dc.identifier.issue3en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage301en_US
dc.identifier.urihttps://doi.org/10.1016/j.phytol.2011.05.008
dc.identifier.urihttps://hdl.handle.net/11454/46043
dc.identifier.volume4en_US
dc.identifier.wosWOS:000296534500021en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofPhytochemistry Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGalanthus trojanusen_US
dc.subjectAmaryllidaceaeen_US
dc.subjectAntimalarial activityen_US
dc.subjectAlkaloid N-oxidesen_US
dc.titleAntiprotozoal alkaloids from Galanthus trojanusen_US
dc.typeArticleen_US

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