Poly (?-caprolactone)-CTAB montmorillonite-silver nanoparticles: A hybrid electrospun nanofibers for in vitro antibacterial activity

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dc.contributor.authorAbayt, Fatma Merve
dc.contributor.authorYalcinkaya, Esra Evrim
dc.date.accessioned2024-08-31T07:50:04Z
dc.date.available2024-08-31T07:50:04Z
dc.date.issued2024
dc.departmentEge Üniversitesien_US
dc.description.abstractElectrospun nanofibers endowed with efficient antibacterial properties have found widespread biomedical applications. Poly (epsilon-caprolactone) (PCL) nanofibers are one of the most popular due to their distinct mechanical and chemical properties, especially in biotechnological applications. Herein, PCL hybrid electrospun nanofibers were fabricated successfully via the electrospinning method, and preparation parameters were optimized at various concentrations of cetyltrimethylammonium bromide (CTAB)-modified montmorillonite (CTAB-Mt) and silver nanoparticles (AgNP) as a nanofillers for the first time. The nanofibers were characterized using SEM, FTIR, XPS, diameter distribution and contact angle measurements. It was found that 0.5% (w/w) CTAB-Mt and 1.0% AgNP (w/w) in the 15% (w/w) in PCL nanofiber is an ideal condition to obtain bead-free and uniform polymer nanofibers. Finally, based on the disc diffusion method, the antibacterial properties of nanofibers were tested against four Gram-negative and Gram-positive bacteria. The cytotoxic nature of the PCL hybrid nanofiber was studied against SV-40 cells using resazurin assay.en_US
dc.description.sponsorshipEge University Scientific Research Projects Coordination Unit; Ege University Planning and Monitoring Coordination of Organizational Development and Directorate of Library and Documentationen_US
dc.description.sponsorshipThe authors would like to thank to Prof. Dr. Dilek Odac & imath; for her valuable helps and using Electrospinning unit. We are grateful to Ege University Planning and Monitoring Coordination of Organizational Development and Directorate of Library and Documentation for their support in editing and proofreading service of this study.en_US
dc.identifier.doi10.1557/s43578-024-01287-8
dc.identifier.endpage1010en_US
dc.identifier.issn0884-2914
dc.identifier.issn2044-5326
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85184272912en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage992en_US
dc.identifier.urihttps://doi.org/10.1557/s43578-024-01287-8
dc.identifier.urihttps://hdl.handle.net/11454/105105
dc.identifier.volume39en_US
dc.identifier.wosWOS:001158356400004en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringer Heidelbergen_US
dc.relation.ispartofJournal of Materials Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240831_Uen_US
dc.subjectPoly (Epsilon-Caprolactone)en_US
dc.subjectElectrospun Nanofibersen_US
dc.subjectSilver Nanoparticlesen_US
dc.subjectMontmorilloniteen_US
dc.subjectAntibacterial Activityen_US
dc.subjectCytotoxicityen_US
dc.titlePoly (?-caprolactone)-CTAB montmorillonite-silver nanoparticles: A hybrid electrospun nanofibers for in vitro antibacterial activityen_US
dc.typeArticleen_US

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