Folic acid-modified clay: targeted surface design for cell culture applications

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dc.contributor.authorBongartz, Rebecca
dc.contributor.authorAg, Didem
dc.contributor.authorSeleci, Muharrem
dc.contributor.authorWalter, Johanna-G.
dc.contributor.authorYalcinkaya, Esra E.
dc.contributor.authorDemirkol, Dilek Odaci
dc.contributor.authorStahl, Frank
dc.contributor.authorTimur, Suna
dc.contributor.authorScheper, Thomas
dc.date.accessioned2019-10-27T21:43:34Z
dc.date.available2019-10-27T21:43:34Z
dc.date.issued2013
dc.departmentEge Üniversitesien_US
dc.description.abstractHere we report the preparation, characterization and application of folic acid modified Montmorillonite clay (FA-Mont) as a cell culture material. Clays exhibit unique properties such as good mechanical and chemical stabilities, high surface area, low toxicity and easy combination with functional organic groups. FA was used as a modifier to facilitate adhesion of folate positive cells on the clay surface. FA-Mont was characterized using FT-IR, XRD, zeta potential measurements as well as thermogravimetric analyses. Finally, the usage potential of FA-Mont as a receptor mediated cell adhesion material was successfully proved by using folate receptor (FR) rich HeLa and FR poor A-549 cells. The cell adhesion studies were monitored and imaged by fluorescence and scanning electron microscopy techniques.en_US
dc.identifier.doi10.1039/c2tb00328g
dc.identifier.endpage528en_US
dc.identifier.issn2050-750X
dc.identifier.issn2050-7518
dc.identifier.issn2050-750Xen_US
dc.identifier.issn2050-7518en_US
dc.identifier.issue4en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage522en_US
dc.identifier.urihttps://doi.org/10.1039/c2tb00328g
dc.identifier.urihttps://hdl.handle.net/11454/47109
dc.identifier.volume1en_US
dc.identifier.wosWOS:000314788600014en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherRoyal Soc Chemistryen_US
dc.relation.ispartofJournal of Materials Chemistry Ben_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.titleFolic acid-modified clay: targeted surface design for cell culture applicationsen_US
dc.typeArticleen_US

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