Our Single Center Experiences with Left Ventricular Assist Device Exchange

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dc.authorscopusid57205137616
dc.authorscopusid57189350968
dc.authorscopusid40661114300
dc.authorscopusid57191909085
dc.authorscopusid7003267009
dc.authorscopusid6603386914
dc.contributor.authorErgi, D.G.
dc.contributor.authorKahraman, Ü.
dc.contributor.authorBalcıoğlu, Ö.
dc.contributor.authorYağmur, B.
dc.contributor.authorYağdı, T.
dc.contributor.authorÖzbaran, M.
dc.date.accessioned2024-08-25T18:32:09Z
dc.date.available2024-08-25T18:32:09Z
dc.date.issued2023
dc.departmentEge Üniversitesien_US
dc.description.abstractBackground: Mechanical circulatory support technology continues to evolve to satisfy the needs of advanced heart failure patients. Despite improvements, various problems occur frequently, and surgical exchange of the pump can be a feasible treatment option. Optimal patient selection is key to success in exchange operations. Methods: Using a retrospective observational cohort design, this study aims to evaluate preoperative profiles and clinical courses of patients' undergoing a device exchange operation and identified possible contributors to in-hospital mortality. Currently, 155 left ventricular assist device (LVAD) patients are being followed up in our program. In total, 15 of 155 patients underwent a pump exchange operation. Baseline characteristics, clinical features, and laboratory results were evaluated. The primary outcome was all-cause in-hospital mortality. Results: Of the 15 patients who underwent a pump exchange operation, thrombosis was the primary cause in 12. Five patients experienced in-hospital mortality within 30 days of LVAD exchange. The international normalized ratio (INR) was higher in patients who experienced in-hospital mortality (2.4 [±0.6] vs 1.2 [±0.4], P = .005) than in patients who survived to discharge. In addition, preoperative lactate levels were significantly higher in patients who died within 30 days (2.9 [±2.6] vs 0.9 [±0.4], P = .019). Conclusions: Higher INR and lactate levels could possibly contribute to in-hospital mortality, which underlines the importance of right ventricular function in this patient population. Careful evaluation of the right heart function is of great importance before exchange operations, and preoperative hemodynamic stability is crucial for better postoperative outcomes. © 2023 Elsevier Inc.en_US
dc.description.sponsorshipAll the authors declare no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. The authors gratefully acknowledge Mrs. Derya Kayıhan and all VAD coordinators for their cooperation in the excellent care and follow-up of LVAD patients in our center.en_US
dc.identifier.doi10.1016/j.transproceed.2023.03.027
dc.identifier.issn0041-1345
dc.identifier.scopus2-s2.0-85153794443en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.urihttps://doi.org/10.1016/j.transproceed.2023.03.027
dc.identifier.urihttps://hdl.handle.net/11454/100146
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Inc.en_US
dc.relation.ispartofTransplantation Proceedingsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.snmz20240825_Gen_US
dc.titleOur Single Center Experiences with Left Ventricular Assist Device Exchangeen_US
dc.typeArticleen_US

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