Two novel saponins from Cephalaria davisiana (Dipsacaceae)

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dc.contributor.authorKayce, Peyker
dc.contributor.authorSarikahya, Nazli Boke
dc.contributor.authorKirmizigul, Suheyla
dc.date.accessioned2019-10-27T22:12:31Z
dc.date.available2019-10-27T22:12:31Z
dc.date.issued2014
dc.departmentEge Üniversitesien_US
dc.description.abstractTwo novel hederagenin type triterpene saponins, namely davisianoside A (1) and davisianoside B (2) together with ten known compounds (3-12) were isolated from the aerial parts of Cephalaria davisiana (Dipsacaceae). One new prosapogenin (1a) was also obtained after the alkaline hydrolysis of compound 1. The chemical structures of all compounds were established mainly by 1D-, 2D-NMR and HR-ESI/MS analysis as well as chemical methods. The antibacterial and antifungal effects of compounds 1-2 were evaluated against Gram-positive, Gram-negative bacteria and unicellular yeast C. albicans by MIC method. (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.en_US
dc.description.sponsorshipResearch Grant Office of Ege University Izmir-TurkeyEge University [2013/Fen/035]; TUBITAKTurkiye Bilimsel ve Teknolojik Arastirma Kurumu (TUBITAK) [BIDEB 2211-A]en_US
dc.description.sponsorshipThe authors would like to thank to Research Grant Office of Ege University Izmir-Turkey (2013/Fen/035) for financial support, to Prof. Dr. H. Sumbul and Assoc. Prof. Dr. R. S. Gokturk for collection and identification of the plant and to Assoc. Prof. Dr. I. Yasa for antimicrobial activity studies. Thanks are also due to TUBITAK (Marmara Research Centre, Gebze, Kocaeli, Turkey) for NMR and HR-ESI/MS analysis and ARGE-FAR (Ege University, Bornova, Izmir, Turkey) for GC-MS analysis. Kayce is grateful to TUBITAK BIDEB 2211-A for the research fellowship programme.en_US
dc.identifier.doi10.1016/j.phytol.2014.07.006
dc.identifier.endpage329en_US
dc.identifier.issn1874-3900
dc.identifier.issn1876-7486
dc.identifier.issn1874-3900en_US
dc.identifier.issn1876-7486en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage324en_US
dc.identifier.urihttps://doi.org/10.1016/j.phytol.2014.07.006
dc.identifier.urihttps://hdl.handle.net/11454/49474
dc.identifier.volume10en_US
dc.identifier.wosWOS:000347915800083en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Science Bven_US
dc.relation.ispartofPhytochemistry Lettersen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectDavisianoside Aen_US
dc.subjectDavisianoside Ben_US
dc.subjectDipsacaceaeen_US
dc.subjectCephalaria davisianaen_US
dc.subjectSaponinen_US
dc.subjectAntimicrobial activityen_US
dc.titleTwo novel saponins from Cephalaria davisiana (Dipsacaceae)en_US
dc.typeArticleen_US

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