Glutathione (GSH) Determination by a Very Simple Electrochemical Method

Basit Öğe Kaydı
dc.contributor.authorSezginturk, Mustafa Kemal
dc.contributor.authorDinckaya, Erhan
dc.date.accessioned2019-10-27T21:24:06Z
dc.date.available2019-10-27T21:24:06Z
dc.date.issued2011
dc.departmentEge Üniversitesien_US
dc.description.abstractGlutathione (GSH; gamma-glutamylcysteinylglycine) is ubiquitous in mammalian and other living cells. It contains an unusual peptide linkage between the amine group of cysteine and the carboxyl group of the glutamate side chain. It has several important functions, including protection against oxidative stress. It is synthesized from its constituent amino acids by the consecutive actions of gamma-glutamylcysteine synthetase and GSH synthetase. Cellular levels of GSH may be increased by supplying substrates and GSH delivery compounds. Increasing cellular GSH may be therapeutically useful. In this study, we investigated the applicability of the glassy carbon electrode coated with thin Hg film layer to the determination of reduced glutathione (GSH). For this purpose, firstly, Hg coating process parameters were studied such as concentration of mercury coating solution, coating current, coating temperature. Then, working conditions were investigated. At the end of these studies, we concluded that although some of limitations, the sensor would be applicable to the determination of reduced glutathione.en_US
dc.identifier.doi10.1007/s10989-011-9243-2
dc.identifier.endpage92en_US
dc.identifier.issn1573-3149
dc.identifier.issn1573-3149en_US
dc.identifier.issue2en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage87en_US
dc.identifier.urihttps://doi.org/10.1007/s10989-011-9243-2
dc.identifier.urihttps://hdl.handle.net/11454/44359
dc.identifier.volume17en_US
dc.identifier.wosWOS:000293235700002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherSpringeren_US
dc.relation.ispartofInternational Journal of Peptide Research and Therapeuticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectGlutathioneen_US
dc.subjectThin Hg filmsen_US
dc.subjectGSHen_US
dc.subjectBiosensoren_US
dc.subjectMercury film electrodeen_US
dc.titleGlutathione (GSH) Determination by a Very Simple Electrochemical Methoden_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu